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Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] E-AB-F1192A

Uniprot : Q8TDQ0
  • Cat.No.:E-AB-F1192A

  • Reactivity: Mouse

To Purchase E-AB-F1192A

Size:
  • 25 μg
  • 100 μg
Price: $85
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Antigen Details

Alternate Names TIM3, TIMD3,HAVcr-2,TIMD-3
Swissprot Q8TDQ0
References
1. Hafler DA and Kuchroo V. 2008. J. Exp. Med. 205:2699.
2. Zhu C, et al. 2005. Nat. Immunol. 6:1245.
3. Wang F, et al. 2009. Immunobiology 214:342.

Product Details

Form Liquid
Clone No. RMT3-23(See Other Available Formats)
Host Rat
Isotype Rat IgG2a, κ
Isotype Control Purified Rat IgG2a, κ Isotype Control[2A3] [Product E-AB-F09833A]
Reactivity Mouse
Application FCM (See the Application Description)
Storage Buffer PBS with 0.05% Proclin300
Recommended Use Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8℃. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation Unconjugated

Background

CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

Protocols & Troubleshootings

Related Protocols Staining Cell Surface Targets for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Cat.No. Product Name Sizes
E-AB-F11920 AF/LE Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] E-AB-F11920 50 μg, 500 μg, 1 mg
E-AB-F1192A Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] E-AB-F1192A 25 μg, 100 μg
E-AB-F1192D PE Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] E-AB-F1192D 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1192E APC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] E-AB-F1192E 20 Tests, 50 Tests, 100 Tests
E-AB-F1192UD PE Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] E-AB-F1192UD 25 μg, 50 μg, 100 μg, 200 μg
E-AB-F1192UE APC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] E-AB-F1192UE 25 μg, 50 μg, 100 μg, 200 μg

Citations

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