|Alternate Names||TIM3, TIMD3,HAVcr-2,TIMD-3|
1. Hafler DA and Kuchroo V. 2008. J. Exp. Med. 205:2699.
2. Zhu C, et al. 2005. Nat. Immunol. 6:1245.
3. Wang F, et al. 2009. Immunobiology 214:342.
|Clone No.||RMT3-23(See Other Available Formats)|
|Isotype||Rat IgG2a, κ|
|Isotype Control||Purified Rat IgG2a, κ Isotype Control[2A3] [Product E-AB-F09833A]|
|Application||FCM (See the Application Description)|
|Storage Buffer||PBS with 0.05% Proclin300|
|Recommended Use||Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.|
|Shipping||Biological ice pack at 4℃|
|Stability & Storage||Keep as concentrated solution.
Store at 2~8℃. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
|CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.|
|Related Protocols||Staining Cell Surface Targets for Flow Cytometry|
|E-AB-F11920||AF/LE Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] E-AB-F11920||50 μg, 500 μg, 1 mg|
|E-AB-F1192A||Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] E-AB-F1192A||25 μg, 100 μg|
|E-AB-F1192D||PE Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] E-AB-F1192D||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1192E||APC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] E-AB-F1192E||20 Tests, 50 Tests, 100 Tests|
|E-AB-F1192UD||PE Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] E-AB-F1192UD||25 μg, 50 μg, 100 μg, 200 μg|
|E-AB-F1192UE||APC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] E-AB-F1192UE||25 μg, 50 μg, 100 μg, 200 μg|
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