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QuicKey Pro Human IL-6(Interleukin 6) ELISA Kit

Citations(304)Uniprot : P05231

  • Cat.No.:E-OSEL-H0001

  • Reactivity: Human

To Purchase E-OSEL-H0001

Size:
  • 96T
  • 48T
  • 24T
  • 96T*5
  • 96T*10
Price: $520
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Get more sensitive and precise results with saving at least 1-2h comparing to traditional ELISA Kits. The new developed technology in house will help to accelerate your science research in a more efficient way.

Product Details

Properties

Assay type Sandwich-ELISA
Format 96T/48T/24
Assay time 1.5h
Detection range 3.13-200 pg/mL
Sensitivity 1.02 pg/mL
Sample type &Sample volume serum and plasma; 50μL
Specificity This kit recognizes IL-6 in samples. No significant cross-reactivity or interference between IL-6 and analogues was observed.
Reproducibility Both intra-CV and inter-CV are < 10%.
Application This ELISA kit applies to the in vitro quantitative determination of IL-6 concentrations in serum and plasma.

Test Principle

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human IL-6. Samples (or Standards) and Horseradish Peroxidase (HRP) linked antibody specific for Human IL-6 are added to the micro ELISA plate wells. Human IL-6 in samples (or standards) combines with the coated antibody and HRP linked detection antibody specific to IL-6. Excess conjugate and unbound sample or standard are washed from the plate. The substrate solution is added to each well. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450±2 nm. The concentration of Human IL-6 in the samples is then determined by comparing the OD of the samples to the standard curve.

Kit components & Storage

An unopened kit can be stored at 2-8℃ for 6 months. After test, the unused wells and reagents should be stored according to the table.
ItemSpecificationsStorage
Micro ELISA Plate(Dismountable) 96T: 8 wells ×12 strips
48T: 8 wells ×6 strips
24T: 8 wells ×3 strips
96T*5: 5 plates, 96T 		2-8℃, 1 months
Reference Standard 96T: 2 vials
48T/24T: 1 vial
96T*5: 10 vials 		2-8℃, use the reconstituted standard within 24h
Concentrated HRP Linked Detection Ab(100×) 96T: 1 vial, 60 μL
48T/24T: 1 vial, 30 μL
96T*5: 5 vials, 60 μL 		2-8℃(Protect from light)
Reference Standard & Sample Diluent 96T/48T/24T: 1 vial, 20 mL
96T*5: 5 vials, 20 mL		 2-8℃
HRP Linked Ab Diluent 96T/48T/24T: 1 vial, 14 mL
96T*5: 5 vials, 14 mL
Concentrated Wash Buffer(25×) 96T/48T/24T: 1 vial, 30 mL
96T*5: 5 vials, 30 mL
Substrate Reagent 96T/48T/24T: 1 vial, 10 mL
96T*5: 5 vials, 10 mL		 2-8℃(Protect from light)
Stop Solution 96T/48T/24T: 1 vial, 10 mL
96T*5: 5 vials, 10 mL		 2-8℃
Plate Sealer 96T/48T/24T: 5 pieces
96T*5: 25 pieces
Product Description 1 copy
Certificate of Analysis 1 copy

Technical Data

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level IL-6 were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level IL-6 were tested on 3 different plates, 20 replicates in each plate.

  Intra-assay Precision Inter-assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean (pg/mL) 9.10 22.29 90.92 9.12 21.98 90.28
Standard deviation 0.57 1.13 3.32 0.53 1.31 3.25
CV (%) 6.24 5.06 3.65 5.84 5.98 3.60

Recovery

The recovery of IL-6 spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 89-102 96
EDTA plasma(n=8) 92-105 97

Linearity

Samples were spiked with high concentrations of Human IL-6 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

Target Information

Database LinksSwissProt: P05231
SynonymsInterleukin 6,IL6, BSF2, HGF, HSF, IFNB2, CDF
Research AreaCancer, Metabolism, Immunology, Neuroscience

Assay Procedures

Citations

  1. Molecular Cancer (2021) IF: 27.401
    KDM6A-ARHGDIB axis blocks metastasis of bladder cancer by inhibiting Rac1

    DOI: 10.1186/s12943-021-01369-9

    PMID: 34006303

    		 Sample: Cell culture supernatant
  2. HEPATOLOGY (2020) IF: 17.425
    Increased Liver Localization of Lipopolysaccharides in Human and Experimental NAFLD

    DOI: 10.1002/hep.31056

    PMID: 31808577

    		 Sample: Serum
  3. ACS Nano (2017) IF: 13.942
    Overcoming the Heat Endurance of Tumor Cells by Interfering with the Anaerobic Glycolysis Metabolism for Improved Photothermal Therapy

    DOI: 10.1021/acsnano.6b06658
    Sample: Cell culture supernatant
  4. Advanced Fiber Materials (2023) IF: 12.958
    Double-Layer Nanofibrous Sponge Tube via Electrospun Fiber and Yarn for Promoting Urethral Regeneration

    DOI: 10.1007/s42765-022-00252-6
    Sample: Human foreskin fibroblasts (HFFs),HSF cell
  5. Theranostics (2021) IF: 11.556
    A SCID mouse-human lung xenograft model of SARS-CoV-2 infection

    DOI: 10.7150/thno.58321

    PMID: 33995679

    		 Sample: Tissue homogenate
  6. ACS Applied Materials & Interfaces (2022) IF: 10.383
    Light-Mediated 3D Printing of Micro-Pyramid-Decorated Tailorable Wound Dressings with Endogenous Growth Factor Sequestration for Improved Wound Healing

    DOI: 10.1021/acsami.2c16418
    Sample: THP-1 cell
  7. THROMBOSIS RESEARCH (2022) IF: 10.407
    High mobility group box 1 derived mainly from platelet microparticles exacerbates microvascular obstruction in no reflow

    DOI: 10.1016/j.thromres.2022.12.003
    Sample: Human cardiac microvascular endothelial cells (HCM
  8. JOURNAL OF NANOBIOTECHNOLOGY (2022) IF: 10.435
    Biodegradable MoSe2-polyvinylpyrrolidone nanoparticles with multi-enzyme activity for ameliorating acute pancreatitis

    DOI: 10.1186/s12951-022-01288-x

    PMID: 35248068

    		 Sample: serum
  9. SCIENCE OF THE TOTAL ENVIRONMENT (2022) IF: 10.753
    Combined effect of polystyrene microplastics and bisphenol A on the human embryonic stem cells-derived liver organoids: The hepatotoxicity and lipid accumulation

    DOI: 10.1016/j.scitotenv.2022.158585

    PMID: 36089014

    		 Sample: liver organoids (LOs)
  10. CELLULAR AND MOLECULAR LIFE SCIENCES (2021) IF: 9.2609
    Chronic exposure to Cytolethal Distending Toxin (CDT) promotes a cGAS-dependent type I interferon response

    DOI: 10.1007/s00018-021-03902-x

    PMID: 34308492

    		 Sample: HeLa-S3 cells
  11. ENVIRONMENTAL POLLUTION (2022) IF: 9.988
    Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line

    DOI: 10.1016/j.envpol.2022.120217

    PMID: 36155221

    		 Sample: HMC3 cell
  12. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 8.025
    Physicochemical properties and protective effects on UVA-induced photoaging in Hs68 cells of Pleurotus ostreatus polysaccharides by fractional precipitation

    DOI: 10.1016/j.ijbiomac.2022.12.254
    Sample: Hs68 cell
  13. ACS Applied Materials & Interfaces (2019) IF: 8.456
    Red Blood Cells-Derived Vesicles for Delivery of Lipophilic Drug Camptothecin

    DOI: 10.1021/acsami.9b04827
    Sample: THP-1 cells
  14. Frontiers in Immunology (2022) IF: 8.786
    METTL3 inhibits inflammation of retinal pigment epithelium cells by regulating NR2F1 in an m6A-dependent manner

    DOI: 10.3389/fimmu.2022.905211

    PMID: 35936005

    		 Sample: RPE cell
  15. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2023) IF: 7.129
    Acute liver injury induced by carbon tetrachloride reversal by Gandankang aqueous extracts through nuclear factor erythroid 2-related factor 2 signaling pathway

    DOI: 10.1016/j.ecoenv.2023.114527
    Sample: HepG2 cell
  16. JOURNAL OF INVESTIGATIVE DERMATOLOGY (2020) IF: 7.143
    MicroRNA-101-3p Downregulates TLR2 Expression, Leading to Reduction in Cytokine Production by Treponema pallidum–Stimulated Macrophages

    DOI: 10.1016/j.jid.2019.12.012
    Sample: plasma,THP-1 cell
  17. JOURNAL OF HEADACHE AND PAIN (2021) IF: 7.277
    HMGB1, NLRP3, IL-6 and ACE2 levels are elevated in COVID-19 with headache: a window to the infection-related headache mechanism

    DOI: 10.1186/s10194-021-01306-7

    PMID: 34384355

    		 Sample: serum
  18. Oxidative Medicine and Cellular Longevity (2022) IF: 7.31
    Change in Oxidative Stress and Mitochondrial Dynamics in Response to Elevated Cold-Inducible RNA-Binding Protein in Cardiac Surgery-Associated Acute Kidney Injury

    DOI: 10.1155/2022/3576892

    PMID: 35855864

    		 Sample: serum
  19. Oxidative Medicine and Cellular Longevity (2022) IF: 7.31
    Antidyslipidemic, Antioxidant, and Anti-inflammatory Effects of Jelly Drink Containing Polyphenol-Rich Roselle Calyces Extract and Passion Fruit Juice with Pulp in Adults with Dyslipidemia: A Randomized, Double-Blind, Placebo-Controlled Trial.

    DOI: 10.1155/2022/4631983
    Sample: plasma
  20. BIOMEDICINE & PHARMACOTHERAPY (2023) IF: 7.419
    Stiff substrates inhibit collagen accumulation via integrin α2β1, FAK and Src kinases in human atrial fibroblast and myofibroblast cultures derived from patients with aortal stenosis

    DOI: 10.1016/j.biopha.2023.114289
    Sample: cardiac fibroblast
  21. Journal of Intensive Care (2023) IF: 7.52
    Predictive value of soluble CD59 for poor 28-day neurological prognosis and all-cause mortality in patients after cardiopulmonary resuscitation: a prospective observatory study

    DOI: 10.1186/s40560-023-00653-8
    Sample: serum
  22. Frontiers in Immunology (2022) IF: 7.561
    TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage-Related Neutrophilic Inflammation in Asthma.

    DOI: 10.3389/fimmu.2022.883885
    Sample: THP-1 monocytes
  23. Frontiers in Immunology (2021) IF: 7.561
    Lactobacillus plantarum CCFM1143 Alleviates Chronic Diarrhea via Inflammation Regulation and Gut Microbiota Modulation: A Double-Blind, Randomized, Placebo-Controlled Study

    DOI: 10.3389/fimmu.2021.746585

    PMID: 34721416

    		 Sample: serum
  24. Antioxidants (2022) IF: 7.675
    Golgi Phosphoprotein 3 Mediates Radiation-Induced Bystander Effect via ERK/EGR1/TNF-α Signal Axis

    DOI: 10.3390/antiox11112172
  25. Antioxidants (2022) IF: 7.675
    Genipin Attenuates Diabetic Cognitive Impairment by Reducing Lipid Accumulation and Promoting Mitochondrial Fusion via FABP4/Mfn1 Signaling in Microglia

    DOI: 10.3390/antiox12010074
    Sample: HMC3 cells
  26. Nanoscale (2021) IF: 7.79
    Rational design of a prodrug to inhibit self-inflammation for cancer treatment

    DOI: 10.1039/D1NR00132A

    PMID: 33710220

    		 Sample: Serum,Cell culture supernatant(dendritic cells,4T1
  27. Marine Drugs (2023) IF: 6.085
    Mechanisms of Antitumor Invasion and Metastasis of the Marine Fungal Derivative Epi-Aszonalenin A in HT1080 Cells

    DOI: 10.3390/md21030156
    Sample: HT1080 cell
  28. Frontiers in Cellular Neuroscience (2022) IF: 6.147
    The SARS-CoV-2 envelope protein disrupts barrier function in an in vitro human blood-brain barrier model.

    DOI: 10.3389/fncel.2022.897564
    Sample: HCMEC/D3 cell,U87MG cell
  29. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208
    Protective Effects of Atractylodis lancea Rhizoma on Lipopolysaccharide-Induced Acute Lung Injury via TLR4/NF-κB and Keap1/Nrf2 Signaling Pathways In Vitro and In Vivo

    DOI: 10.3390/ijms232416134
    Sample: THP-1 cells
  30. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208
    In Vitro Evaluation of Anti-Inflammatory and Protective Potential of an Extract from Cornus mas L. Fruit against H2O2-Induced Oxidative Stress in Human Skin Keratinocytes and Fibroblasts

    DOI: 10.3390/ijms232213755
  31. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208
    Fermented Taiwanofungus camphoratus Extract Ameliorates Psoriasis-Associated Response in HaCaT Cells via Modulating NF-𝜅B and mTOR Pathways

    DOI: 10.3390/ijms232314623
  32. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2021) IF: 6.291
    Novel insights into the role of BRD4 in fine particulate matter induced airway hyperresponsiveness

    DOI: 10.1016/j.ecoenv.2021.112440

    PMID: 34175826

    		 Sample: hASMCs cells
  33. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2021) IF: 6.291
    miR-122–5p regulates hepatocytes damage caused by BaP and DBP co-exposure through SOCS1/STAT3 signaling in vitro

    DOI: 10.1016/j.ecoenv.2021.112570
    Sample: L02 cell
  34. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2022) IF: 6.291
    GSDMD-miR-223-NLRP3 axis involved in B(a)P-induced inflammatory injury of alveolar epithelial cells

    DOI: 10.1016/j.ecoenv.2022.113286

    PMID: 35144130

    		 Sample: A549 cell
  35. Food & Function (2022) IF: 6.317
    Whole grain germinated brown rice regulates intestinal immune homeostasis and gastrointestinal hormones in type 2 diabetic patients—a randomized control trial

    DOI: 10.1039/D2FO00477A
    Sample: serum
  36. Pharmaceutics (2021) IF: 6.321
    Comparative Study of the Pharmacological Properties and Biological Effects of Polygonum aviculare L. herba Extract-Entrapped Liposomes versus Quercetin-Entrapped Liposomes on Doxorubicin-Induced Toxicity on HUVECs

    DOI: 10.3390/pharmaceutics13091418

    PMID: 34575493

    		 Sample: HUVEC
  37. Pharmaceutics (2022) IF: 6.525
    In Vitro Antibacterial and Anti-Inflammatory Activity of Arctostaphylos uva-ursi Leaf Extract against Cutibacterium acnes

    DOI: 10.3390/pharmaceutics14091952

    PMID: 36145700

    		 Sample: HaCaT cell
  38. Oxidative Medicine and Cellular Longevity (2021) IF: 6.543
    Autophagic Degradation of Gasdermin D Protects against Nucleus Pulposus Cell Pyroptosis and Retards Intervertebral Disc Degeneration In Vivo

    DOI: 10.1155/2021/5584447

    PMID: 34239691

    		 Sample: NP cells
  39. Frontiers in Nutrition (2022) IF: 6.59
    Different oral and gut microbial profiles in those with Alzheimer's disease consuming anti-inflammatory diets.

    DOI: 10.3389/fnut.2022.974694
    Sample: serum
  40. PHYTOMEDICINE (2022) IF: 6.656
    Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro

    DOI: 10.1016/j.phymed.2022.154339

    PMID: 35870375

    		 Sample: MH7A cell
  41. Frontiers in Cell and Developmental Biology (2021) IF: 6.684
    Fexofenadine Protects Against Intervertebral Disc Degeneration Through TNF Signaling

    DOI: 10.3389/fcell.2021.687024
    Sample: NP cell
  42. Frontiers in Cell and Developmental Biology (2020) IF: 6.684
    EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma

    DOI: 10.3389/fcell.2020.574940

    PMID: 33363140

    		 Sample: Tissue homogenate
  43. Nutrients (2022) IF: 6.706
    Alteration in Gut Microbiota Associated with Zinc Deficiency in School-Age Children

    DOI: 10.3390/nu14142895

    PMID: 35889856

    		 Sample: serum
  44. Sports Medicine-Open (2019) IF: 6.766
    The Effects of a Single Versus Three Consecutive Sessions of Football Training on Postprandial Lipemia: a Randomized, Controlled Trial in Healthy, Recreationally Active Males

    DOI: 10.1186/s40798-019-0212-1
    Sample: serum
  45. Journal of Inflammation Research (2021) IF: 6.922
    Silenced SNHG1 Inhibited Epithelial-Mesenchymal Transition and Inflammatory Response of ARPE-19 Cells Induced by High Glucose

    DOI: 10.2147/JIR.S299010
    Sample: ARPE-19 cell
  46. Journal of Inflammation Research (2021) IF: 6.922
    Inflammation and Insulin Resistance in a Group of Sub-Saharan African Women with Polycystic Ovary Syndrome

    DOI: 10.2147/JIR.S313193
    Sample: plasma
  47. Journal of Inflammation Research (2021) IF: 6.922
    Anti-Inflammatory Effects of Four Psilocybin-Containing Magic Mushroom Water Extracts in vitro on 15-Lipoxygenase Activity and on Lipopolysaccharide-Induced Cyclooxygenase-2 and Inflammatory Cytokines in Human U937 Macrophage Cells

    DOI: 10.2147/JIR.S317182
    Sample: U937 cell
  48. Antioxidants (2020) IF: 5.014
    Oxidative Stress and Pro-Inflammatory Status in Patients with Non-Alcoholic Fatty Liver Disease

    DOI: 10.3390/antiox9080759
    Sample: plasma
  49. LIFE SCIENCES (2022) IF: 5.037
    STING up-regulates VEGF expression in oxidative stress-induced senescence of retinal pigment epithelium via NF-κB/HIF-1α pathway

    DOI: 10.1016/j.lfs.2021.120089

    PMID: 35007563

    		 Sample: ARPE-19 cell
  50. CELL PROLIFERATION (2019) IF: 5.039
    Inhibition of CREB‐mediated ZO‐1 and activation of NF‐κB‐induced IL‐6 by colonic epithelial MCT4 destroys intestinal barrier function

    DOI: 10.1111/cpr.12673
    Sample: CaCO2 cells，HT‐29 cell
  51. Frontiers in Medicine (2021) IF: 5.093
    METTL3 Promotes Activation and Inflammation of FLSs Through the NF-κB Signaling Pathway in Rheumatoid Arthritis

    DOI: 10.3389/fmed.2021.607585

    PMID: 34295905

    		 Sample: synovial
  52. LIVER INTERNATIONAL (2020) IF: 5.175
    Fontan protein‐losing enteropathy is associated with advanced liver disease and a proinflammatory intestinal and systemic state

    DOI: 10.1111/liv.14375
    Sample: Plasma
  53. CHEMICO-BIOLOGICAL INTERACTIONS (2021) IF: 5.194
    A novel glyceroglycolipid from brown algae Ishige okamurae improve photoaging and counteract inflammation in UVB-induced HaCaT cells

    DOI: 10.1016/j.cbi.2021.109737

    PMID: 34740599

    		 Sample: HaCaT cells
  54. JOURNAL OF ETHNOPHARMACOLOGY (2023) IF: 5.195
    Comparison study of Beninese and Chinese herbal medicines in treating COVID-19

    DOI: 10.1016/j.jep.2023.116172
    Sample: BEAS-2B cell
  55. CLINICAL SCIENCE (2020) IF: 5.223
    Effects of circulating extracellular microvesicles from spinal cord-injured adults on endothelial cell function

    DOI: 10.1042/CS20200047

    PMID: 32219341

    		 Sample: Cell culture supernatant
  56. Scientific Reports (2016) IF: 5.228
    TLR3-/4-Priming Differentially Promotes Ca 2+ Signaling and Cytokine Expression and Ca 2+ -Dependently Augments Cytokine Release in hMSCs

    DOI: 10.1038/srep23103
    Sample: Cell culture supernatant
  57. Frontiers in Molecular Biosciences (2021) IF: 5.246
    CYP11A1 Upregulation Leads to Trophoblast Oxidative Stress and Fetal Neurodevelopmental Toxicity That can be Rescued by Vitamin D

    DOI: 10.3389/fmolb.2020.608447

    PMID: 33659272

    		 Sample: Cell culture supernatant(BeWo cells (CCL-98,ATCC))
  58. Biomaterials Science (2019) IF: 5.251
    Silk fibroin-alginate based beads for human mesenchymal stem cell differentiation in 3D

    DOI: 10.1039/C9BM01000A
    Sample: THP-1 cells
  59. COLLOIDS AND SURFACES B-BIOINTERFACES (2021) IF: 5.268
    Electrospun nanoyarn and exosomes of adipose-derived stem cells for urethral regeneration: Evaluations in vitro and in vivo

    DOI: 10.1016/j.colsurfb.2021.112218

    PMID: 34801930

    		 Sample: HFFs cells,HSFs cells
  60. Frontiers in Cellular and Infection Microbiology (2021) IF: 5.293
    GLUT3 as an Intersection of Glycerophospholipid Metabolism and the Innate Immune Response to Candida albicans

    DOI: 10.3389/fcimb.2021.648988
    Sample: THP-1 cells
  61. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2017) IF: 5.31
    The classic signalling and trans‐signalling of interleukin‐6 are both injurious in podocyte under high glucose exposure

    DOI: 10.1111/jcmm.13314
    Sample: Serum
  62. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021) IF: 5.31
    Downregulation of p300/CBP-associated factor inhibits cardiomyocyte apoptosis via suppression of NF-κB pathway in ischaemia/reperfusion injury rats

    DOI: 10.1111/jcmm.16959

    PMID: 34601814

    		 Sample: myocardial tissue,blood
  63. Food & Function (2022) IF: 5.396
    A randomised, double-blind, placebo-controlled trial of Bifidobacterium bifidum CCFM16 for manipulation of gut microbiota and relief from chronic constipation

    DOI: 10.1039/D1FO03896F
    Sample: serum
  64. OSTEOARTHRITIS AND CARTILAGE (2018) IF: 5.454
    Associations between knee structural measures, circulating inflammatory factors and MMP13 in patients with knee osteoarthritis

    DOI: 10.1016/j.joca.2018.05.003
    Sample: Serum
  65. JOURNAL OF CELLULAR PHYSIOLOGY (2020) IF: 5.546
    Cytokine physiognomies of MSCs from varied sources confirm the regenerative commitment post-coculture with activated neutrophils

    DOI: 10.1002/jcp.29713

    PMID: 32385929

    		 Sample: Cell culture supernatant
  66. Molecular Therapy-Nucleic Acids (2018) IF: 5.66
    miR-93-5p-Containing Exosomes Treatment Attenuates Acute Myocardial Infarction-Induced Myocardial Damage

    DOI: 10.1016/j.omtn.2018.01.010
    Sample: serum
  67. Aging-US (2022) IF: 5.682
    The TLR4/NF-κB/MAGI-2 signaling pathway mediates postoperative delirium

    DOI: 10.18632/aging.203955
    Sample: plasma,cerebrospinal fluid
  68. INTERNATIONAL IMMUNOPHARMACOLOGY (2022) IF: 5.714
    CircVAPA contributes to hyper-proliferation and inflammation of keratinocytes through miR-125b-5p/sirt6 axis in psoriasis

    DOI: 10.1016/j.intimp.2022.109632
    Sample: HaCaT cells
  69. ENVIRONMENTAL POLLUTION (2019) IF: 5.714
    Activation of NF-κB pathways mediating the inflammation and pulmonary diseases associated with atmospheric methylamine exposure

    DOI: 10.1016/j.envpol.2019.06.059

    PMID: 31252119

    		 Sample: Cell culture supernatant
  70. Nutrients (2021) IF: 5.719
    Relationship between 25 Hydroxyvitamin D, Overweight/Obesity Status, Pro-Inflammatory and Oxidative Stress Markers in Patients with Type 2 Diabetes: A Simplified Empirical Path Model

    DOI: 10.3390/nu13082889

    PMID: 34445049

    		 Sample: serum
  71. WORLD JOURNAL OF GASTROENTEROLOGY (2016) IF: 5.742
    Inhibitory effect of miR-125b on hepatitis C virus core protein-induced TLR2/MyD88 signaling in THP-1 cells

    DOI: 10.3748/wjg.v22.i17.4354
    Sample: Cell culture supernatant
  72. CHEMOSPHERE (2020) IF: 5.778
    PM2.5 organic extract mediates inflammation through the ERβ pathway to contribute to lung carcinogenesis in vitro and vivo

    DOI: 10.1016/j.chemosphere.2020.127867
    Sample: Cell culture supernatant
  73. Frontiers in Pharmacology (2021) IF: 5.811
    Traditional Chinese Medicine, Qingfei Paidu Decoction and Xuanfei Baidu Decoction, Inhibited Cytokine Production via NF-κB Signaling Pathway in Macrophages: Implications for Coronavirus Disease 2019 (COVID-19) Therapy

    DOI: 10.3389/fphar.2021.722126
    Sample: THP-1 cell
  74. ACS Applied Materials & Interfaces (2014) IF: 5.9
    Flexible Gold Electrode Array for Multiplexed Immunoelectrochemical Measurement of Three Protein Biomarkers for Prostate Cancer

    DOI: 10.1021/am505726b
    Sample: Serum
  75. CLINICAL ORAL IMPLANTS RESEARCH (2021) IF: 5.977
    Notch down-regulation and inflammatory cytokines and RANKL overexpression involvement in peri-implant mucositis and peri-implantitis: A cross-sectional study

    DOI: 10.1111/clr.13850

    PMID: 34546593

    		 Sample: peri-implant crevicular fluid
  76. Frontiers in Pharmacology (2022) IF: 5.988
    MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation

    DOI: 10.3389/fphar.2022.978587

    PMID: 36091773

    		 Sample: U87 cell
  77. Frontiers in Pharmacology (2022) IF: 5.988
    Aconiti lateralis radix praeparata total alkaloids exert anti-RA effects by regulating NF-κB and JAK/STAT signaling pathways and promoting apoptosis.

    DOI: 10.3389/fphar.2022.980229
    Sample: MH7A cell
  78. NEPHROLOGY DIALYSIS TRANSPLANTATION (2021) IF: 5.992
    Effect of fructooligosaccharide on endothelial function in CKD patients: a randomized controlled trial

    DOI: 10.1093/ndt/gfaa335
    Sample: serum
  79. COLLOIDS AND SURFACES B-BIOINTERFACES (2023) IF: 5.999
    Multifunctional barrier membranes promote bone regeneration by scavenging H2O2, generating O2, eliminating inflammation, and regulating immune response

    DOI: 10.1016/j.colsurfb.2023.113147
    Sample: periodontal ligament stem cells (PDLSCs)
  80. Pediatric Obesity (2021) IF: 4
    The effects of Mediterranean diet on hepatic steatosis, oxidative stress, and inflammation in adolescents with non-alcoholic fatty liver disease: A randomized controlled trial

    DOI: 10.1111/ijpo.12872

    PMID: 34881510

    		 Sample: serum
  81. American Journal of Translational Research (2021) IF: 4.06
    Minimally-invasive stone removal in urinary calculi patients during pregnancy: clinical therapeutic effects and low complications

    PMID: 34540086

    		 Sample: serum
  82. American Journal of Translational Research (2021) IF: 4.06
    Long non-coding RNA H19 as a diagnostic marker in peripheral blood of patients with sepsis

    PMID: 34017457

    		 Sample: Serum
  83. American Journal of Translational Research (2021) IF: 4.06
    Effect of levetiracetam in combination with topiramate on immune function, cognitive function, and neuronal nutritional status of children with intractable epilepsy

    PMID: 34650715

    		 Sample: serum
  84. ORAL DISEASES (2022) IF: 4.068
    Lycium barbarum polysaccharide-glycoprotein promotes osteogenesis in hPDLSCs via ERK activation

    DOI: 10.1111/odi.14409
    Sample: hPDLSCs
  85. INFLAMMATION (2022) IF: 4.092
    LncRNA FLG-AS1 Mitigates Diabetic Retinopathy by Regulating Retinal Epithelial Cell Inflammation, Oxidative Stress, and Apoptosis via miR-380-3p/SOCS6 Axis

    DOI: 10.1007/s10753-022-01665-6

    PMID: 35461393

    		 Sample: ARPE-19 cell
  86. INFLAMMATION (2022) IF: 4.092
    CircOAS3 Regulates Keratinocyte Proliferation and Psoriatic Inflammation by Interacting with Hsc70 via the JNK/STAT3/NF-κB Signaling Pathway

    DOI: 10.1007/s10753-022-01664-7

    PMID: 35307784

    		 Sample: HaCaT cell
  87. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2022) IF: 4.098
    Identification of polycystic ovary syndrome from blood serum using hormone levels via Raman spectroscopy and multivariate analysis

    DOI: 10.1016/j.saa.2022.121029

    PMID: 35217265

    		 Sample: serum
  88. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2021) IF: 4.101
    A functional polymorphism at the miR‑491‑5p binding site in the 3'‑untranslated region of the MMP‑9 gene increases the risk of developing ventilator‑associated pneumonia

    DOI: 10.3892/ijmm.2021.5050

    PMID: 34664683

    		 Sample: peripheral blood
  89. ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119
    LncRNA MEG3 ameliorates NiO nanoparticles-induced pulmonary inflammatory damage via suppressing the p38 mitogen activated protein kinases pathway

    DOI: 10.1002/tox.23464

    PMID: 35006638

    		 Sample: A549 cell
  90. ENVIRONMENTAL TOXICOLOGY (2021) IF: 4.119
    Limonin ameliorates acute pancreatitis by suppressing JAK2/STAT3 signaling pathway

    DOI: 10.1002/tox.23352

    PMID: 34423886

    		 Sample: serum
  91. JOURNAL OF CLINICAL PERIODONTOLOGY (2019) IF: 4.164
    Effects of non‐surgical periodontal therapy on inflammatory markers of psoriasis: A randomized controlled trial

    DOI: 10.1111/jcpe.13205
    Sample: saliva
  92. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020) IF: 4.192
    Changes in Allergenicity of Ovalbumin in Vitro and in Vivo on Conjugation with Quercetin

    DOI: 10.1021/acs.jafc.0c00461

    PMID: 32182051

    		 Sample: Serum,Cell culture supernatant
  93. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2021) IF: 4.223
    Occupational exposure of rural workers to pesticides in a vegetable-producing region in Brazil

    DOI: 10.1007/s11356-021-12444-5

    PMID: 33469792

    		 Sample: Plasma
  94. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2021) IF: 4.223
    Biochemical investigation of human exposure to aflatoxin M1 and its association with risk factors of diabetes mellitus

    DOI: 10.1007/s11356-021-14871-w

    PMID: 34216342

    		 Sample: serum
  95. Frontiers in Pharmacology (2020) IF: 4.225
    NRF2 -617 C/A Polymorphism Impacts Proinflammatory Cytokine Levels, Survival, and Transplant-Related Mortality After Hematopoietic Stem Cell Transplantation in Adult Patients Receiving Busulfan-Based Conditioning Regimens

    DOI: 10.3389/fphar.2020.563321

    PMID: 33384597

    		 Sample: plasma
  96. Frontiers in Pharmacology (2020) IF: 4.225
    Network Pharmacology-Based Strategy to Investigate the Pharmacologic Mechanisms of Atractylodes macrocephala Koidz. for the Treatment of Chronic Gastritis

    DOI: 10.3389/fphar.2019.01629

    PMID: 32063848

    		 Sample: Cell culture supernatant
  97. JOURNAL OF ORAL PATHOLOGY & MEDICINE (2019) IF: 4.253
    Elevated leptin levels in temporomandibular joint osteoarthritis promote proinflammatory cytokine IL‐6 expression in synovial fibroblasts

    DOI: 10.1111/jop.12819
    Sample: Cell culture supernatant
  98. Scientific Reports (2017) IF: 4.259
    Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis

    DOI: 10.1038/s41598-017-14808-9
    Sample: tuberculous pleural effusion
  99. VIROLOGICA SINICA (2021) IF: 4.327
    Expansion of GARP-Expressing CD4+CD25−FoxP3+ T Cells and SATB1 Association with Activation and Coagulation in Immune Compromised HIV-1-Infected Individuals in South Africa

    DOI: 10.1007/s12250-021-00386-8
    Sample: Plasma
  100. Epigenomics (2023) IF: 4.357
    Low-dose 5-aza-2′-deoxycytidine protects against early renal injury by increasing klotho expression

    DOI: 10.2217/epi-2022-0430
    Sample: Serum,HK-2 cell
  101. DRUG DEVELOPMENT RESEARCH (2021) IF: 4.36
    CircTHBS1 facilitates the progression of interstitial cystitis depending on the regulation of miR-139-5p/MFN2 axis

    DOI: 10.1002/ddr.21864

    PMID: 34368980

    		 Sample: serum
  102. JOURNAL OF ETHNOPHARMACOLOGY (2021) IF: 4.36
    Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways

    DOI: 10.1016/j.jep.2021.114791

    PMID: 34737112

    		 Sample: MH7A cell
  103. Scientific Reports (2021) IF: 4.38
    Red blood cell transfusion induces abnormal HIF-1α response to cytokine storm after adult cardiac surgery

    DOI: 10.1038/s41598-021-01695-4

    PMID: 34782683

    		 Sample: serum
  104. PLoS Neglected Tropical Diseases (2021) IF: 4.411
    Anaphylatoxins orchestrate Th17 response via interactions between CD16+ monocytes and pleural mesothelial cells in tuberculous pleural effusion

    DOI: 10.1371/journal.pntd.0009508

    PMID: 34237073

    		 Sample: pleural fluid
  105. JOURNAL OF PERIODONTAL RESEARCH (2022) IF: 4.419
    Slit guidance ligand 2 promotes the inflammatory response of periodontitis through activation of the NF-κB signaling pathway

    DOI: 10.1111/jre.12987

    PMID: 35426130

    		 Sample: gingival crevicular fluid (GCF),Human gingival fib
  106. EUROPEAN JOURNAL OF PHARMACOLOGY (2019) IF: 4.432
    Salidroside ameliorates endothelial inflammation and oxidative stress by regulating the AMPK/NF-κB/NLRP3 signaling pathway in AGEs-induced HUVECs

    DOI: 10.1016/j.ejphar.2019.172797
    Sample: HUVECs cells
  107. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020) IF: 4.486
    The stiffness‐controlled release of interleukin‐6 by cardiac fibroblasts is dependent on integrin α2β1

    DOI: 10.1111/jcmm.15974
    Sample: Cell culture supernatant
  108. BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
    Long non-coding RNA NNT-AS1 regulates proliferation, apoptosis, inflammation and airway remodeling of chronic obstructive pulmonary disease via targeting miR-582-5p/FBXO11 axis

    DOI: 10.1016/j.biopha.2020.110326
    Sample: Cell culture supernatant
  109. BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
    LncRNA SNHG5 regulates cell apoptosis and inflammation by miR-132/PTEN axis in COPD

    DOI: 10.1016/j.biopha.2020.110016

    PMID: 32145584

    		 Sample: Cell culture supernatant
  110. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020) IF: 4.556
    Short-Term Physiological Effects of a Very Low-Calorie Ketogenic Diet: Effects on Adiponectin Levels and Inflammatory States

    DOI: 10.3390/ijms21093228
    Sample: serum
  111. Frontiers in Genetics (2022) IF: 4.599
    ILF2 Contributes to Hyperproliferation of Keratinocytes and Skin Inflammation in a KLHDC7B-DT-Dependent Manner in Psoriasis

    DOI: 10.3389/fgene.2022.890624
    Sample: keratinocytes
  112. Frontiers in Neuroscience (2021) IF: 4.677
    Kernelized k-Local Hyperplane Distance Nearest-Neighbor Model for Predicting Cerebrovascular Disease in Patients With End-Stage Renal Disease

    DOI: 10.3389/fnins.2021.773208

    PMID: 34759797

    		 Sample: serum
  113. MEDIATORS OF INFLAMMATION (2020) IF: 4.711
    IL-37 Exerts Anti-Inflammatory Effects in Fetal Membranes of Spontaneous Preterm Birth via the NF-κB and IL-6/STAT3 Signaling Pathway

    DOI: 10.1155/2020/1069563
    Sample: Cell culture supernatant
  114. BIOINORGANIC CHEMISTRY AND APPLICATIONS (2022) IF: 4.724
    Silver Nanoparticles Stabilized by Poly (Vinyl Pyrrolidone) with Potential Anticancer Activity towards Prostate Cancer

    DOI: 10.1155/2022/6181448

    PMID: 36248627

    		 Sample: PC3 cell,HSF cell
  115. Clinical Epidemiology (2021) IF: 4.79
    Cardiovascular Disease Prediction by Machine Learning Algorithms Based on Cytokines in Kazakhs of China

    DOI: 10.2147/CLEP.S313343

    PMID: 34135637

    		 Sample: blood
  116. JOURNAL OF PSYCHIATRIC RESEARCH (2022) IF: 4.791
    Comparison of cognitive impairments with lipid profiles and inflammatory biomarkers in unipolar and bipolar depression

    DOI: 10.1016/j.jpsychires.2022.04.002

    PMID: 35429740

    		 Sample: serum
  117. Journal of Immunology Research (2021) IF: 4.818
    Remote Inflammatory Preconditioning Alleviates Lipopolysaccharide-Induced Acute Lung Injury via Inhibition of Intrinsic Apoptosis in Rats

    DOI: 10.1155/2021/1125199

    PMID: 34595242

    		 Sample: serum
  118. BIOCONJUGATE CHEMISTRY (2017) IF: 4.818
    Multifunctional Dextran Sulfate-Coated Reconstituted High Density Lipoproteins Target Macrophages and Promote Beneficial Antiatherosclerotic Mechanisms

    DOI: 10.1021/acs.bioconjchem.6b00600
    Sample: Cell culture supernatant
  119. Journal of Immunology Research (2021) IF: 4.818
    Moesin Is a Novel Biomarker of Endothelial Injury in Sepsis

    DOI: 10.1155/2021/6695679

    PMID: 33628853

    		 Sample: Cell culture supernatant(HMECs)
  120. Cells (2018) IF: 4.829
    Mesenchymal Stem Cells (MSCs) Coculture Protects [Ca2+]i Orchestrated Oxidant Mediated Damage in Differentiated Neurons In Vitro

    DOI: 10.3390/cells7120250
    Sample: Cell culture supernatant
  121. Oxidative Medicine and Cellular Longevity (2019) IF: 4.868
    Resveratrol Inhibits MMP3 and MMP9 Expression and Secretion by Suppressing TLR4/NF-κB/STAT3 Activation in Ox-LDL-Treated HUVECs

    DOI: 10.1155/2019/9013169
    Sample: Cell culture supernatant
  122. JOURNAL OF IMMUNOLOGY (2020) IF: 4.886
    CALML6 Controls TAK1 Ubiquitination and Confers Protection against Acute Inflammation

    DOI: 10.4049/jimmunol.1901042

    PMID: 32303555

    		 Sample: Cell culture supernatant
  123. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2022) IF: 4.925
    Potential Therapeutic Activity of Berberine in Thyroid-Associated Ophthalmopathy: Inhibitory Effects on Tissue Remodeling in Orbital Fibroblasts

    DOI: 10.1167/iovs.63.10.6

    PMID: 36094643

    		 Sample: Orbital fibroblasts (OFs)
  124. MOLECULES (2022) IF: 4.927
    Modulatory Effect of Diosmin and Diosmetin on Metalloproteinase Activity and Inflammatory Mediators in Human Skin Fibroblasts Treated with Lipopolysaccharide

    DOI: 10.3390/molecules27134264

    PMID: 35807509

    		 Sample: human fibroblast cell
  125. INTERNATIONAL IMMUNOPHARMACOLOGY (2019) IF: 4.932
    Arsenic trioxide improves Treg and Th17 balance by modulating STAT3 in treatment-naïve rheumatoid arthritis patients

    DOI: 10.1016/j.intimp.2019.05.001
    Sample: PBMCs cells
  126. INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
    Altered kynurenine pathway metabolism in patients with ankylosing spondylitis

    DOI: 10.1016/j.intimp.2021.108018

    PMID: 34358860

    		 Sample: serum
  127. PPAR Research (2021) IF: 4.964
    PPAR-Alpha Agonist Fenofibrate Combined with Octreotide Acetate in the Treatment of Acute Hyperlipidemia Pancreatitis

    DOI: 10.1155/2021/6629455

    PMID: 33968146

    		 Sample: Serum
  128. PPAR Research (2019) IF: 4.964
    Arsenic Trioxide in Synergy with Vitamin D Rescues the Defective VDR-PPAR- Functional Module of Autophagy in Rheumatoid Arthritis

    DOI: 10.1155/2019/6403504
    Sample: rheumatoid arthritis (RA) fibroblast-like synovioc
  129. European Review for Medical and Pharmacological Sciences (2020) IF: 3.024
    MiR-942-5p alleviates septic acute kidney injury by targeting FOXO3.

    DOI: 10.26355/eurrev_202006_21521
    Sample: Cell culture supernatant
  130. Pharmacological Reports (2021) IF: 3.027
    The association of the quality of sleep with proinflammatory cytokine profile in inflammatory bowel disease patients

    DOI: 10.1007/s43440-021-00333-0

    PMID: 34694623

    		 Sample: serum
  131. NEUROSCIENCE LETTERS (2022) IF: 3.046
    Role of CD36 rs1761667 AA genotype in the expression of inflammatory cytokines and Parkinson’s disease progression: A case-control study in a northern Han Chinese population

    DOI: 10.1016/j.neulet.2022.136736
    Sample: plasma
  132. MOLECULES (2019) IF: 3.06
    Effect of Diosmin Administration in Patients with Chronic Venous Disorders on Selected Factors Affecting Angiogenesis

    DOI: 10.3390/molecules24183316
    Sample: serum
  133. American Journal of Translational Research (2018) IF: 3.061
    LncRNA MALAT1 promotes relapse of breast cancer patients with postoperative fever

    PMID: 30416660

    		 Sample: plasma
  134. INFLAMMATION RESEARCH (2019) IF: 3.061
    Common variants of genes encoding TLR4 and TLR4 pathway members TIRAP and IRAK1 are effective on MCP1, IL6, IL1β, and TNFα levels in type 2 diabetes and insulin resistance

    DOI: 10.1007/s00011-019-01263-7
    Sample: serum
  135. MOLECULAR IMMUNOLOGY (2019) IF: 3.064
    IL-16 regulates macrophage polarization as a target gene of mir-145-3p

    DOI: 10.1016/j.molimm.2018.12.027

    PMID: 30634164

    		 Sample: Cell lysate
  136. Oncology Letters (2022) IF: 3.111
    A role for serum cytokines and cell adhesion molecules in the non‑invasive diagnosis of colorectal cancer

    DOI: 10.3892/ol.2022.13443
    Sample: serum
  137. INTERNATIONAL IMMUNOPHARMACOLOGY (2018) IF: 3.118
    Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism

    DOI: 10.1016/j.intimp.2018.10.013
    Sample: HepG2 cells
  138. IUBMB LIFE (2015) IF: 3.143
    TSG attenuates LPC‐induced endothelial cells inflammatory damage through notch signaling inhibition

    DOI: 10.1002/iub.1458
    Sample: Cell culture supernatant
  139. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy (2021) IF: 3.168
    Inflammatory Biomarkers Levels in T2DM Emirati Patients with Diabetic Neuropathy

    DOI: 10.2147/DMSO.S319863

    PMID: 34345175

    		 Sample: serum
  140. LIFE SCIENCES (2018) IF: 3.234
    LncRNA PMS2L2 protects ATDC5 chondrocytes against lipopolysaccharide-induced inflammatory injury by sponging miR-203

    DOI: 10.1016/j.lfs.2018.12.020

    PMID: 30550887

    		 Sample: Cell culture supernatant
  141. DIABETES RESEARCH AND CLINICAL PRACTICE (2019) IF: 3.239
    Effect of Ramadan diurnal fasting on visceral adiposity and serum adipokines in overweight and obese individuals

    DOI: 10.1016/j.diabres.2019.05.023

    PMID: 31150725

    		 Sample: Serum
  142. PLoS One (2013) IF: 3.24
    Oxidative Burst of Circulating Neutrophils Following Traumatic Brain Injury in Human

    DOI: 10.1371/journal.pone.0068963
    Sample: Plasma
  143. PLoS One (2022) IF: 3.24
    Clinical characteristics and outcomes of COVID-19 patients in Bali, Indonesia

    DOI: 10.1371/journal.pone.0269026

    PMID: 35687545

    		 Sample: serum
  144. Bioengineered (2022) IF: 3.269
    Transcriptome analysis of eutopic endometrial stromal cells in women with adenomyosis by RNA-sequencing

    DOI: 10.1080/21655979.2022.2077614

    PMID: 35603555

    		 Sample: A-EuESCs,N-ESCs
  145. Bioengineered (2022) IF: 3.269
    Nintedanib ameliorates oxidized low-density lipoprotein -induced inflammation and cellular senescence in vascular endothelial cells

    DOI: 10.1080/21655979.2022.2036913

    PMID: 35236245

    		 Sample: HUVECs
  146. Bioengineered (2022) IF: 3.269
    Dihydroartemisinin targets fibroblast growth factor receptor 1 (FGFR1) to inhibit interleukin 17A (IL-17A)-induced hyperproliferation and inflammation of keratinocytes

    DOI: 10.1080/21655979.2021.2021701

    PMID: 35006038

    		 Sample: HaCaT cell
  147. Bioengineered (2022) IF: 3.269
    Circ_0001897 regulates high glucose-induced angiogenesis and inflammation in retinal microvascular endothelial cells through miR-29c-3p/transforming growth factor beta 2 axis

    DOI: 10.1080/21655979.2022.2070997

    PMID: 35510503

    		 Sample: Human retinal microvascular endothelial cell (HREC
  148. Bioengineered (2021) IF: 3.269
    Carvedilol activates nuclear factor E2-related factor 2/ antioxidant response element pathway to inhibit oxidative stress and apoptosis of retinal pigment epithelial cells induced by high glucose

    DOI: 10.1080/21655979.2021.2012627

    PMID: 34898371

    		 Sample: ARPE-19 cell
  149. Bioengineered (2021) IF: 3.269
    Apremilast mitigates interleukin (IL)-13-induced inflammatory response and mucin production in human nasal epithelial cells (hNECs)

    DOI: 10.1080/21655979.2021.1987818

    PMID: 34607526

    		 Sample: Human nasal epithelial cells (hNECs)
  150. NEW JOURNAL OF CHEMISTRY (2020) IF: 3.288
    The development of an ultra-sensitive electrochemical immunosensor using a PPyr-NHS functionalized disposable ITO sheet for the detection of interleukin 6 in real human serums

    DOI: 10.1039/D0NJ03183F
    Sample: serum
  151. CELLULAR IMMUNOLOGY (2019) IF: 3.291
    DosR antigen Rv1737c induces activation of macrophages dependent on the TLR2 pathway

    DOI: 10.1016/j.cellimm.2019.103947
    Sample: THP-1 cells
  152. JOURNAL OF MOLECULAR ENDOCRINOLOGY (2018) IF: 3.297
    ADSC-conditioned media elicit an ex vivo anti-inflammatory macrophage response

    DOI: 10.1530/JME-18-0078
    Sample: Serum,Cell culture medium
  153. FISH & SHELLFISH IMMUNOLOGY (2019) IF: 3.298
    The first cloned echinoderm tumor necrosis factor receptor from Holothuria leucospilota: Molecular characterization and functional analysis

    DOI: 10.1016/j.fsi.2019.08.008

    PMID: 31394160

    		 Sample: Cell culture supernatant
  154. COMPLEMENTARY THERAPIES IN MEDICINE (2022) IF: 3.335
    Comparison of delta-tocotrienol and alpha-tocopherol effects on hepatic steatosis and inflammatory biomarkers in patients with non-alcoholic fatty liver disease: A randomized double-blind active-controlled trial

    DOI: 10.1016/j.ctim.2022.102866

    PMID: 35933083

    		 Sample: serum
  155. MEDICAL MICROBIOLOGY AND IMMUNOLOGY (2021) IF: 3.402
    Long non-coding RNA NEAT1 promotes lipopolysaccharide-induced injury in human tubule epithelial cells by regulating miR-93-5p/TXNIP axis

    DOI: 10.1007/s00430-021-00705-6

    PMID: 33885954

    		 Sample: Cell culture supernatant
  156. Journal of Medical Biochemistry (2022) IF: 3.402
    Cul4a attenuates LPS-induced acute kidney injury via blocking NF-kB signaling pathway in sepsis

    DOI: 10.5937/jomb0-33096
    Sample: HK-2 cell
  157. Biomed Research International (2021) IF: 3.411
    Iron Status in Newly Diagnosed β-Thalassemia Major: High Rate of Iron Status due to Erythropoiesis Drive

    DOI: 10.1155/2021/5560319

    PMID: 33954177

    		 Sample: Serum
  158. JOURNAL OF CELLULAR BIOCHEMISTRY (2019) IF: 3.448
    Eriodictyol inhibits survival and inflammatory responses and promotes apoptosis in rheumatoid arthritis fibroblast‐like synoviocytes through AKT/FOXO1 signaling

    DOI: 10.1002/jcb.28724
    Sample: rheumatoid arthritis (RA) fibroblast-like synovioc
  159. SHOCK (2021) IF: 3.454
    The Value of Extracellular Cold-Inducible RNA-Binding Protein (eCIRP) in Predicting the Severity and Prognosis of Patients After Cardiac Arrest: A Preliminary Observational Study

    DOI: 10.1097/SHK.0000000000001702

    PMID: 34276038

    		 Sample: serum
  160. JOURNAL OF NEUROIMMUNOLOGY (2022) IF: 3.478
    Association between pro-inflammatory cytokines in cerebrospinal fluid and headache in patients with aneurysmal subarachnoid hemorrhage

    DOI: 10.1016/j.jneuroim.2022.577841

    PMID: 35279426

    		 Sample: cerebrospinal fluid (CSF)
  161. Journal of Personalized Medicine (2022) IF: 3.508
    The Role of Plasma Interleukin-6 Levels on Atherosclerotic Cardiovascular Disease and Cardiovascular Mortality Risk Scores in Javanese Patients with Chronic Kidney Disease

    DOI: 10.3390/jpm12071122

    PMID: 35887619

    		 Sample: plasma
  162. Journal of Personalized Medicine (2022) IF: 3.508
    NLRP6 Induces Lung Injury and Inflammation Early in Brucella and Influenza Coinfection

    DOI: 10.3390/jpm12122063
    Sample: lung tissues
  163. MEDIATORS OF INFLAMMATION (2019) IF: 3.545
    Nomogram Based on Cytokines for Cardiovascular Diseases in Xinjiang Kazakhs

    DOI: 10.1155/2019/4756295
    Sample: plasma
  164. MEDIATORS OF INFLAMMATION (2018) IF: 3.549
    Grape Seed Proanthocyanidin Extract Inhibits Human Esophageal Squamous Cancerous Cell Line ECA109 via the NF-κB Signaling Pathway

    DOI: 10.1155/2018/3403972
    Sample: ECA109 cells
  165. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2022) IF: 3.568
    Bradykinin/bradykinin 1 receptor promotes brain microvascular endothelial cell permeability and proinflammatory cytokine release by downregulating Wnt3a

    DOI: 10.1002/jbt.23213

    PMID: 36111657

    		 Sample: serum,hBMECs
  166. Nanoscale Research Letters (2020) IF: 3.578
    Nec-1 Attenuates Neurotoxicity Induced by Titanium Dioxide Nanomaterials on Sh-Sy5y Cells Through RIP1

    DOI: 10.1186/s11671-020-03300-5
    Sample: SH-SY5Y cell
  167. PHYTOMEDICINE (2018) IF: 3.61
    Ethanolic extract of Kaempferia parviflora interrupts the mechanisms-associated rheumatoid arthritis in SW982 culture model via p38/STAT1 and STAT3 pathways

    DOI: 10.1016/j.phymed.2018.11.015

    PMID: 31005814

    		 Sample: Cell culture supernatant
  168. CLINICAL BIOCHEMISTRY (2022) IF: 3.625
    Expression of Nrf2 protein in serum of patients with rheumatoid arthritis: A novel indicator for disease activity and disease prognosis

    DOI: 10.1016/j.clinbiochem.2022.12.011
    Sample: serum
  169. APOPTOSIS (2015) IF: 3.685
    strain FP10

    DOI: 10.1007/s10495-015-1162-9
    Sample: Cell culture supernatant
  170. BIOLOGICAL TRACE ELEMENT RESEARCH (2021) IF: 3.738
    Does the TMPRSS6 C > T Polymorphism Modify the Endurance Training Effects on Hematological Parameters?

    DOI: 10.1007/s12011-021-02876-y
    Sample: serum
  171. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2020) IF: 3.74
    Impact of Lipophilic Versus Hydrophilic Statins on the Clinical Outcome and Biomarkers of Remodeling in Heart Failure Patients: A Prospective Comparative Randomized Study

    DOI: 10.1111/bcp.14695
    Sample: serum
  172. BIOMEDICINE & PHARMACOTHERAPY (2019) IF: 3.743
    Sapylin (OK-432) alters inflammation and angiogenesis in vivo and vitro

    DOI: 10.1016/j.biopha.2019.108706

    PMID: 30844656

    		 Sample: Wound drainage fluid
  173. MEDIATORS OF INFLAMMATION (2020) IF: 3.758
    Diagnostic and Prognostic Value of IL-6 and sTREM-1 in SIRS and Sepsis in Children

    DOI: 10.1155/2020/8201585

    PMID: 32655314

    		 Sample: Serum
  174. SCHIZOPHRENIA RESEARCH (2020) IF: 3.759
    Chronic fatigue and fibromyalgia symptoms are key components of deficit schizophrenia and are strongly associated with activated immune-inflammatory pathways

    DOI: 10.1016/j.schres.2020.05.003

    PMID: 32467068

    		 Sample: Serum
  175. Heliyon (2022) IF: 3.776
    Role of non-neuronal cholinergic system in the early stage response of epithelial-mesenchymal transformation related markers in A549 cells induced by coal particles

    DOI: 10.1016/j.heliyon.2022.e11751
    Sample: A549 cell
  176. INFLAMMOPHARMACOLOGY (2019) IF: 3.838
    Tocilizumab attenuates acute lung and kidney injuries and improves survival in a rat model of sepsis via down-regulation of NF-κB/JNK: a possible role of P-glycoprotein

    DOI: 10.1007/s10787-019-00628-y

    PMID: 31440860

    		 Sample: Serum
  177. TOXICOLOGY LETTERS (2017) IF: 3.858
    MicroRNA-218 acts by repressing TNFR1-mediated activation of NF-κB, which is involved in MUC5AC hyper-production and inflammation in smoking-induced bronchiolitis of COPD

    DOI: 10.1016/j.toxlet.2017.08.079
    Sample: Serum,Cell culture supernatant
  178. PEPTIDES (2022) IF: 3.867
    Interleukin-6, undercarboxylated osteocalcin, and brain-derived neurotrophic factor responses to single and repeated sessions of high-intensity interval exercise

    DOI: 10.1016/j.peptides.2022.170864

    PMID: 36028073

    		 Sample: plasma
  179. RESPIRATORY RESEARCH (2020) IF: 3.924
    Thymosin β10 promotes tumor-associated macrophages M2 conversion and proliferation via the PI3K/Akt pathway in lung adenocarcinoma

    DOI: 10.1186/s12931-020-01587-7
    Sample: THP-1 cell
  180. Annals of Translational Medicine (2021) IF: 3.932
    The liver X receptor agonist T0901317 reduces the inflammation of alveolar epithelial cells induced by polyhexamethylene guanidine through inhibition of the NFκB signaling pathway

    DOI: 10.21037/atm-21-6501
    Sample: A549 cell
  181. Annals of Translational Medicine (2022) IF: 3.932
    Possible causes of atherosclerosis: lncRNA COLCA1 induces oxidative stress in human coronary artery endothelial cells and impairs wound healing

    DOI: 10.21037/atm-22-507
    Sample: HCAECs
  182. Annals of Translational Medicine (2022) IF: 3.932
    Advanced platelet-rich fibrin promotes the paracrine function and proliferation of adipose-derived stem cells and contributes to micro-autologous fat transplantation by modulating HIF-1α and VEGF

    DOI: 10.21037/atm-21-6812
    Sample: adipose-derived stem cell (ASCs)
  183. INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
    Mammalian Ste20-like kinase 4 inhibits the inflammatory response in Aspergillus fumigatus keratitis

    DOI: 10.1016/j.intimp.2020.107021

    PMID: 33182037

    		 Sample: Cell lysate
  184. INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
    Inhibition of HMGB1 involved in the protective of salidroside on liver injury in diabetes mice

    DOI: 10.1016/j.intimp.2020.106987

    PMID: 33217691

    		 Sample: Cell culture supernatant
  185. INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
    IL-38 alleviates the inflammatory response and the degeneration of nucleus pulposus cells via inhibition of the NF-κB signaling pathway in vitro

    DOI: 10.1016/j.intimp.2020.106592

    PMID: 32502922

    		 Sample: Cell culture supernatant
  186. PLoS Neglected Tropical Diseases (2016) IF: 3.948
    Clonorchis sinensis Co-infection Could Affect the Disease State and Treatment Response of HBV Patients

    DOI: 10.1371/journal.pntd.0004806
    Sample: Serum,Cell culture supernatant
  187. NEUROGASTROENTEROLOGY AND MOTILITY (2022) IF: 3.96
    Somatization is associated with altered serum levels of vitamin D, serotonin, and brain-derived neurotrophic factor in patients with predominant diarrhea irritable bowel syndrome

    DOI: 10.1111/nmo.14512
    Sample: serum
  188. NEUROCHEMICAL RESEARCH (2021) IF: 3.996
    Silencing of UCA1 Protects Against MPP+-Induced Cytotoxicity in SK-N-SH Cells via Modulating KCTD20 Expression by Sponging miR-423-5p

    DOI: 10.1007/s11064-020-03214-9
    Sample: Cell culture supernatant
  189. Scientific Reports (2020) IF: 3.998
    Early modulation of macrophage ROS-PPARγ-NF-κB signalling by sonodynamic therapy attenuates neointimal hyperplasia in rabbits

    DOI: 10.1038/s41598-020-68543-9

    PMID: 32669704

    		 Sample: Cell culture supernatant
  190. POULTRY SCIENCE (2019) IF: 2.027
    The effect of different dietary ratios of arginine, methionine, and lysine on the performance, carcass traits, and immune status of turkeys

    DOI: 10.1016/j.psj.2019.10.008

    PMID: 32036960

    		 Sample: Plasma
  191. INTERNATIONAL OPHTHALMOLOGY (2022) IF: 2.029
    Evaluation of serum semaphorin 3A and interleukin 6 levels in patients with pseudoexfoliation syndrome

    DOI: 10.1007/s10792-022-02599-6
    Sample: serum
  192. HUMAN & EXPERIMENTAL TOXICOLOGY (2020) IF: 2.067
    Investigation of DNA damage, oxidative stress, and inflammation in synthetic cannabinoid users:

    DOI: 10.1177/0960327120930057
    Sample: Plasma
  193. Molecular Medicine Reports (2020) IF: 2.1
    Penehyclidine hydrochloride alleviates lipopolysaccharide‑induced acute respiratory distress syndrome in cells via regulating autophagy‑related pathway

    DOI: 10.3892/mmr.2020.11739

    PMID: 33300058

    		 Sample: Cell culture supernatant
  194. AUTOIMMUNITY (2020) IF: 2.125
    Auto-reactivity against gut bacterial peptides in patients with late-onset diabetes

    DOI: 10.1080/08916934.2020.1818232

    PMID: 32924613

    		 Sample: Serum
  195. International Journal of General Medicine (2022) IF: 2.145
    Correlation of Inflammation and Coagulation Markers with the Incidence of Deep Vein Thrombosis in Cancer Patients with High Risk of Thrombosis

    DOI: 10.2147/IJGM.S372038

    PMID: 35898299

    		 Sample: plasma
  196. Sleep and Breathing (2020) IF: 2.162
    Intermittent hypoxia induces tumor immune escape in murine S180 solid tumors via the upregulation of TGF-β 1 in mice

    DOI: 10.1007/s11325-020-02166-2

    PMID: 32840731

    		 Sample: Tissue homogenate
  197. Innate Immunity (2019) IF: 2.173
    Functional characterisation of Holothuria leucospilota Fas-associated death domain in the innate immune-related signalling pathways:

    DOI: 10.1177/1753425919877680
    Sample: Cell culture supernatant
  198. Biomed Research International (2019) IF: 2.197
    Nigella sativa Oil Mouth Rinse Improves Chemotherapy-Induced Oral Mucositis in Patients with Acute Myeloid Leukemia

    DOI: 10.1155/2019/3619357
    Sample: salivary
  199. CORNEA (2020) IF: 2.215
    Galectin-3, IL-1A, IL-6, and EGF Levels in Corneal Epithelium of Patients With Recurrent Corneal Erosion Syndrome

    DOI: 10.1097/ICO.0000000000002422

    PMID: 32732704

    		 Sample: Tissue homogenate
  200. Computational and Mathematical Methods in Medicine (2021) IF: 2.238
    A Self-Representation-Based Fuzzy SVM Model for Predicting Vascular Calcification of Hemodialysis Patients

    DOI: 10.1155/2021/2464821

    PMID: 34367315

    		 Sample: serum
  201. Immunity Inflammation and Disease (2022) IF: 2.239
    Association of the IRAK4 rs4251545 genetic polymorphism with severity of enterovirus-71 infection in Chinese children

    DOI: 10.1002/iid3.614

    PMID: 35478439

    		 Sample: plasma
  202. INTERNATIONAL UROLOGY AND NEPHROLOGY (2022) IF: 2.266
    Evaluation of malnutrition and inflammation after total parathyroidectomy in patients on maintenance dialysis

    DOI: 10.1007/s11255-022-03436-6
    Sample: serum
  203. Trials (2021) IF: 2.279
    Effect of Lycium barbarum polysaccharide supplementation in non-alcoholic fatty liver disease patients: study protocol for a randomized controlled trial

    DOI: 10.1186/s13063-021-05529-6

    PMID: 34521466

    		 Sample: blood
  204. Obesity Research & Clinical Practice (2021) IF: 2.288
    Roles and mechanisms of NRG1 in modulating the pathogenesis of NAFLD through ErbB3 signaling in hepatocytes (NRG1 modulates NAFLD through ErbB3 signaling)

    DOI: 10.1016/j.orcp.2021.01.003

    PMID: 33541789

    		 Sample: Cell culture supernatant
  205. BMC Cardiovascular Disorders (2021) IF: 2.298
    MicroRNA-33-5p inhibits cholesterol efflux in vascular endothelial cells by regulating citrate synthase and ATP-binding cassette transporter A1

    DOI: 10.1186/s12872-021-02228-7

    PMID: 34517822

    		 Sample: VEC
  206. JOURNAL OF MEDICAL VIROLOGY (2021) IF: 2.327
    Evaluation of the relationship between pentraxin 3 (PTX3) rs2305619 (281A/G) and rs1840680 (1449A/G) polymorphisms and the clinical course of COVID-19

    DOI: 10.1002/jmv.27238

    PMID: 34314051

    		 Sample: blood
  207. JOURNAL OF MEDICAL VIROLOGY (2021) IF: 2.327
    Analysis of serum cytokine and protective vitamin D levels in severe cases of COVID-19

    DOI: 10.1002/jmv.27294

    PMID: 34427934

    		 Sample: serum
  208. ACTA ODONTOLOGICA SCANDINAVICA (2019) IF: 2.331
    Leptin induces IL-6 and IL-8 expression through leptin receptor Ob-Rb in human dental pulp fibroblasts

    DOI: 10.1080/00016357.2018.1536280

    PMID: 30600742

    		 Sample: Cell culture supernatant
  209. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2017) IF: 2.341
    Particulate matter 2.5 regulates lipid synthesis and inflammatory cytokine production in human SZ95 sebocytes

    DOI: 10.3892/ijmm.2017.3109
    Sample: Cell culture supernatant
  210. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2020) IF: 2.352
    A case of asthma with Behcet’s disease: successful treatment with omalizumab and its effects on recurrent aphthous lesions

    DOI: 10.1080/08923973.2020.1789656
    Sample: Serum
  211. Journal of Orthopaedic Surgery and Research (2022) IF: 2.359
    Circ_0043947 contributes to interleukin 1β-induced injury in chondrocytes by sponging miR-671-5p to up-regulate RTN3 expression in osteoarthritis pathology

    DOI: 10.1186/s13018-022-02970-4

    PMID: 35331286

    		 Sample: chondrocytes
  212. CARDIOVASCULAR PATHOLOGY (2017) IF: 2.359
    C reactive protein and enzymatically modified LDL cooperatively promote dendritic cell-mediated T cell activation

    DOI: 10.1016/j.carpath.2017.03.009
    Sample: Cell culture supernatant
  213. MOLECULES (2015) IF: 2.416
    Mitochondrion-Targeted Peptide SS-31 Inhibited Oxidized Low-Density Lipoproteins-Induced Foam Cell Formation through both ROS Scavenging and Inhibition of Cholesterol Influx in RAW264.7 Cells

    DOI: 10.3390/molecules201219764
    Sample: Cell lysate
  214. BIOLOGICAL TRACE ELEMENT RESEARCH (2019) IF: 2.431
    Study of Metal-Metal Interactions and Their Biomarkers Using an Intestinal Human Cell Line

    DOI: 10.1007/s12011-019-01831-2

    PMID: 31473895

    		 Sample: Cell lysate
  215. COMPLEMENTARY THERAPIES IN MEDICINE (2022) IF: 2.446
    Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial

    DOI: 10.1016/j.ctim.2022.102819

    PMID: 35240291

    		 Sample: serum
  216. Experimental and Therapeutic Medicine (2021) IF: 2.447
    MicroRNA‑16 regulates lipopolysaccharide‑induced inflammatory factor expression by targeting TLR4 in normal human bronchial epithelial cells

    DOI: 10.3892/etm.2021.10414
    Sample: NHBE cells
  217. Experimental and Therapeutic Medicine (2021) IF: 2.447
    Mediators of extracellular matrix degradation and inflammation: A new team of possible biomarkers for oral squamous cell carcinoma stage

    DOI: 10.3892/etm.2021.10309

    PMID: 34194555

    		 Sample: Oral cancer tissue
  218. Experimental and Therapeutic Medicine (2021) IF: 2.447
    Mangiferin inhibits hypoxia/reoxygenation‑induced alveolar epithelial cell injury via the SIRT1/AMPK signaling pathway

    DOI: 10.3892/etm.2021.10654
    Sample: A549 cell
  219. Translational Pediatrics (2021) IF: 2.488
    Comparison of safety, effectiveness and serum inflammatory factor indexes of Saccharomyces boulardii versus Bifidobacterium triple viable in treating children with chronic diarrhea: a randomized trial

    DOI: 10.21037/tp-21-195
    Sample: serum
  220. DIGESTIVE DISEASES (2020) IF: 2.493
    LncRNA PMS2L2 downregulates miR-24 through methylation to suppress cell apoptosis in ulcerative colitis

    DOI: 10.1159/000513330
    Sample: HCnEpCs
  221. Immunity Inflammation and Disease (2022) IF: 2.493
    Knockdown of LINC01138 protects human chondrocytes against IL-1β-induced damage by regulating the hsa-miR-1207-5p/KIAA0101 axis

    DOI: 10.1002/iid3.744
    Sample: Chondrocytes
  222. ACTA TROPICA (2018) IF: 2.509
    Assessment of chemokine and cytokine signatures in patients with dengue infection: A hospital-based study in Kolkata, India

    DOI: 10.1016/j.actatropica.2018.10.017

    PMID: 30395811

    		 Sample: Serum
  223. BIOSCIENCE REPORTS (2019) IF: 2.535
    Serum profile of cytokines and their genetic variants in metabolic syndrome and healthy subjects: a comparative study

    DOI: 10.1042/BSR20181202
    Sample: serum
  224. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018) IF: 2.559
    Exosomes derived from human umbilical cord mesenchymal stem cells alleviate acute liver failure by reducing the activity of the NLRP3 inflammasome in macrophages

    DOI: 10.1016/j.bbrc.2018.11.189

    PMID: 30528233

    		 Sample: Serum
  225. Neuropsychiatric Disease and Treatment (2021) IF: 2.57
    Interleukin-6 in Cerebrospinal Fluid Small Extracellular Vesicles as a Potential Biomarker for Prognosis of Aneurysmal Subarachnoid Haemorrhage

    DOI: 10.2147/NDT.S304394

    PMID: 34012263

    		 Sample: Cerebrospinal Fluid
  226. Clinical Respiratory Journal (2021) IF: 2.57
    Adhesion molecules as diagnostic and severity biomarkers in pediatric community-acquired pneumonia

    DOI: 10.1111/crj.13334

    PMID: 33484111

    		 Sample: Whole Blood,Serum
  227. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2020) IF: 2.575
    XIST silencing alleviated inflammation and mesangial cells proliferation in diabetic nephropathy by sponging miR-485

    DOI: 10.1080/13813455.2020.1789880

    PMID: 32669002

    		 Sample: Serum
  228. MICROBIAL PATHOGENESIS (2019) IF: 2.581
    Isolation, characterization and analysis of pro-inflammatory potential of Klebsiella pneumoniae outer membrane vesicles

    DOI: 10.1016/j.micpath.2019.103719

    PMID: 31493501

    		 Sample: Cell culture supernatant
  229. Canadian Journal of Infectious Diseases & Medical Microbiology (2022) IF: 2.585
    The Anti-Inflammatory Effect of Callicarpa nudiflora Extract on H. Pylori-Infected GES-1 Cells through the Inhibition of ROS/NLRP3/Caspase-1/IL-1 β Signaling Axis

    DOI: 10.1155/2022/5469236

    PMID: 35873363

    		 Sample: GES-1 cell
  230. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2022) IF: 2.586
    Upregulated NORAD is implicated in apoptosis, inflammation, and oxidative stress in ulcerative colitis through the nuclear factor-κappaB signaling

    DOI: 10.1097/MEG.0000000000002370

    PMID: 35412486

    		 Sample: human normal colonic mucosal cells (FHCs)
  231. Annals of Palliative Medicine (2021) IF: 2.595
    The effects of blood purification combined with antibiotics on extravascular lung water index, inflammatory factors, and prognosis of patients with severe acute pancreatitis complicated with acute respiratory distress syndrome.

    DOI: 10.21037/apm-21-2168
    Sample: blood
  232. Annals of Palliative Medicine (2021) IF: 2.595
    Effect of probiotics supplementation combined with WeChat platform health management on nutritional status, inflammatory factors, and quality of life in patients with mild-to-moderate ulcerative colitis: a randomized trial.

    DOI: 10.21037/apm-21-1056
    Sample: serum
  233. TRANSFUSION AND APHERESIS SCIENCE (2022) IF: 2.596
    CFNAs of RBCs affect the release of inflammatory factors through the expression of CaMKIV in macrophages

    DOI: 10.1016/j.transci.2022.103494
    Sample: macrophages
  234. RENAL FAILURE (2021) IF: 2.606
    Predictors of coronary artery calcification and its association with cardiovascular events in patients with chronic kidney disease

    DOI: 10.1080/0886022X.2021.1953529

    PMID: 34315328

    		 Sample: blood
  235. Dose-Response (2022) IF: 2.623
    Immune Cell and Biochemical Biomarkers in Advanced Laryngeal Cancer:

    DOI: 10.1177/15593258221115537
    Sample: serum
  236. Dose-Response (2022) IF: 2.623
    Correlation of Ionized Magnesium with the Parameters of Oxidative Stress as Potential Biomarkers in Patients with Anxiety and Depression: A Pilot Study:

    DOI: 10.1177/15593258221116741
    Sample: serum
  237. Evidence-based Complementary and Alternative Medicine (2021) IF: 2.63
    The Anti-Inflammatory Effect of Smilax china L. Extract on LPS-Stimulated THP-1 via Downregulation of MAPK and NF-κB Signaling Pathway

    DOI: 10.1155/2021/9958808
    Sample: THP-1 cells
  238. GENE (2019) IF: 2.638
    Downregulation of hsa_circ_0068087 ameliorates TLR4/NF-κB/NLRP3 inflammasome-mediated inflammation and endothelial cell dysfunction in high glucose conditioned by sponging miR-197

    DOI: 10.1016/j.gene.2019.05.012
    Sample: Human Umbilical Vein Endothelial Cells (HUVECs)
  239. Evidence-based Complementary and Alternative Medicine (2022) IF: 2.65
    Febuxostat Alleviates Allergic Rhinitis by Inhibiting Inflammation and Monocyte Adhesion in Human Nasal Epithelial Cells via Regulating KLF6.

    DOI: 10.1155/2022/9092311
    Sample: Human nasal epithelial cell (hNECs)
  240. Evidence-based Complementary and Alternative Medicine (2022) IF: 2.65
    Effect of Thymosin on Inflammatory Factor Levels, Immune Function, and Quality of Life in Lung Cancer Patients Undergoing Radical Thoracoscopic Surgery

    DOI: 10.1155/2022/8749999

    PMID: 35832513

    		 Sample: Serum
  241. ONCOLOGY REPORTS (2017) IF: 2.662
    PLD4 promotes M1 macrophages to perform antitumor effects in colon cancer cells

    DOI: 10.3892/or.2016.5216
    Sample: macrophage
  242. Journal of Stroke & Cerebrovascular Diseases (2022) IF: 2.677
    Circ_0101874 overexpression strengthens PDE4D expression by targeting miR-335-5p to promote neuronal injury in ischemic stroke

    DOI: 10.1016/j.jstrokecerebrovasdis.2022.106817

    PMID: 36252429

    		 Sample: SK-N-SH cells
  243. Journal of Healthcare Engineering (2022) IF: 2.682
    Inhibition of microRNA-665 Alleviates Septic Acute Kidney Injury by Targeting Bcl-2

    DOI: 10.1155/2022/2961187

    PMID: 35281537

    		 Sample: HK-2 cell
  244. Food & Function (2016) IF: 2.686
    Antidiabetic (type 2) effects of Lactobacillus G15 and Q14 in rats through regulation of intestinal permeability and microbiota

    DOI: 10.1039/C6FO00831C
    Sample: Plasma,Serum
  245. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019) IF: 2.705
    Long non-coding RNA MEG3 regulates CSE-induced apoptosis and inflammation via regulating miR-218 in 16HBE cells

    DOI: 10.1016/j.bbrc.2019.10.135

    PMID: 31668807

    		 Sample: Cell culture supernatant
  246. European Review for Medical and Pharmacological Sciences (2019) IF: 2.721
    Plasma concentration of ZCCHC14 contributes to prognostic efficacy in intracerebral hemorrhage patients.

    DOI: 10.26355/eurrev_201910_19167
    Sample: Plasma
  247. BMC Oral Health (2021) IF: 2.757
    The effect of conventional versus electronic cigarette use on treatment outcomes of peri-implant disease

    DOI: 10.1186/s12903-021-01784-w
    Sample: Saliva
  248. BIOMEDICINE & PHARMACOTHERAPY (2017) IF: 2.759
    Oleanolic acid protects against pathogenesis of atherosclerosis, possibly via FXR-mediated angiotensin (Ang)-(1–7) upregulation

    DOI: 10.1016/j.biopha.2017.11.151
    Sample: Cell culture supernatant,Serum
  249. EUROPEAN JOURNAL OF DERMATOLOGY (2022) IF: 2.805
    Role of the long non-coding RNA, SPRR2C, based on an in vitro psoriatic keratinocyte cell model

    DOI: 10.1684/ejd.2022.4247

    PMID: 35866915

    		 Sample: Ker-CT cell,HaCaT cell
  250. PLoS One (2017) IF: 2.806
    High anti-human cytomegalovirus antibody levels are associated with the progression of essential hypertension and target organ damage in Han Chinese population

    DOI: 10.1371/journal.pone.0181440
    Sample: Serum
  251. PLoS One (2017) IF: 2.806
    Depot-specific inflammation with decreased expression of ATM2 in white adipose tissues induced by high-margarine/lard intake

    DOI: 10.1371/journal.pone.0188007
    Sample: Cell culture supernatant
  252. BIOMEDICAL AND ENVIRONMENTAL SCIENCES (2022) IF: 2.831
    Periodontal Ligament Stem Cells Reverse the High Glucose Level-Induced Inflammatory State of Macrophages

    DOI: 10.3967/bes2022.089

    PMID: 35945185

    		 Sample: THP-1 cell
  253. BMC Complementary Medicine and Therapies (2023) IF: 2.838
    Exploration of the mechanism by which Huangqi Guizhi Wuwu decoction inhibits Lps-induced inflammation by regulating macrophage polarization based on network pharmacology

    DOI: 10.1186/s12906-022-03826-4
    Sample: human histiocytic lymphoma (U-937) cell
  254. Dermatologic Therapy (2021) IF: 2.851
    Carotid intima-media thickness and serum proinflammatory cytokine levels in rosacea patients without cardiovascular risk factors

    DOI: 10.1111/dth.14733

    PMID: 33389789

    		 Sample: Serum
  255. HUMAN & EXPERIMENTAL TOXICOLOGY (2022) IF: 2.903
    Fluorometholone inhibits high glucose-induced cellular senescence in human retinal endothelial cells:

    DOI: 10.1177/09603271221076107
    Sample: human retinal endothelial cell
  256. International Journal of Chronic Obstructive Pulmonary Disease (2018) IF: 2.917
    Differential expression of RNA-binding proteins in bronchial epithelium of stable COPD patients

    DOI: 10.2147/COPD.S166284
    Sample: BEAS-2B cells
  257. Genetic Testing and Molecular Biomarkers (2019) IF: 1.121
    Association of PAR-2 Gene Polymorphisms with the Inflammatory Response and Susceptibility to Knee Osteoarthritis in the Chinese Han Population

    DOI: 10.1089/gtmb.2018.0219

    PMID: 30688539

    		 Sample: Synovia
  258. Experimental and Therapeutic Medicine (2017) IF: 1.261
    Inhibition of miR‑27a suppresses the inflammatory response via the p38/MAPK pathway in intervertebral disc cells

    DOI: 10.3892/etm.2017.5053
    Sample: Cell culture supernatant
  259. Experimental and Therapeutic Medicine (2017) IF: 1.261
    Blockade of 146b‑5p promotes inflammation in atherosclerosis‑associated foam cell formation by targeting TRAF6

    DOI: 10.3892/etm.2017.5121
    Sample: macrophages
  260. ANZ JOURNAL OF SURGERY (2020) IF: 1.355
    Effect of laparoscopic sleeve gastrectomy on renal function in obese patients

    DOI: 10.1111/ans.15767

    PMID: 32115876

    		 Sample: Serum,Urine
  261. JAPANESE JOURNAL OF INFECTIOUS DISEASES (2021) IF: 1.362
    Frequency of interleukin-6 rs1800795 (-174G/C) and rs1800797 (-597G/A) polymorphisms in COVID-19 patients in Turkey who develop macrophage activation syndrome

    DOI: 10.7883/yoken.JJID.2021.046

    PMID: 33952771

    		 Sample: serum
  262. International Journal of Clinical and Experimental Pathology (2018) IF: 1.396
    MicroRNA-124 alleviates hyperoxia-induced inflammatory response in pulmonary epithelial cell by inhibiting TLR4/NF-κB/CCL2

    PMID: 31938089

    		 Sample: Beas2B cells
  263. Brazilian Journal of Otorhinolaryngology (2020) IF: 1.405
    Risk factors for medication-related osteonecrosis of the jaw and salivary IL-6 IN cancer patients

    DOI: 10.1016/j.bjorl.2020.09.010

    PMID: 33189595

    		 Sample: Saliva
  264. Experimental and Therapeutic Medicine (2018) IF: 1.41
    Role of miR‑589‑3p in human lumbar disc degeneration and its potential mechanism

    DOI: 10.3892/etm.2017.5593
    Sample: Cell culture supernatant
  265. Experimental and Therapeutic Medicine (2018) IF: 1.41
    N‑methyl pyrrolidone promotes ankle fracture healing by inhibiting inflammation via suppression of the mitogen‑activated protein kinase signaling pathway

    DOI: 10.3892/etm.2018.5842
    Sample: peripheral blood
  266. Experimental and Therapeutic Medicine (2018) IF: 1.41
    Anti‑inflammatory effect of Resolvin D1 on LPS‑treated MG‑63 cells Corrigendum in /10.3892/etm.2019.8021

    DOI: 10.3892/etm.2018.6721
    Sample: Serum
  267. Experimental and Therapeutic Medicine (2019) IF: 1.448
    Short‑term efficacy and safety of prednisone in herpes zoster and the effects on IL‑6 and IL‑10

    DOI: 10.3892/etm.2019.7898
    Sample: serum
  268. Experimental and Therapeutic Medicine (2019) IF: 1.448
    Effects of propofol combined with remifentanil anesthesia on the NO, endothelin and inflammatory cytokines in the plasma of patients with liver cirrhosis during the perioperative period

    DOI: 10.3892/etm.2019.7367

    PMID: 30988754

    		 Sample: Plasma
  269. Journal of Burn Care & Research (2019) IF: 1.538
    Mitochondrial DNA-Induced Inflammatory Responses and Lung Injury in Thermal Injury Murine Model: Protective Effect of Cyclosporine-A

    DOI: 10.1093/jbcr/irz029

    PMID: 30926991

    		 Sample: Serum
  270. MEDICINE (2020) IF: 1.552
    Regulatory role and mechanism of the inhibition of the Mcl-1 pathway during apoptosis and polarization of H37Rv-infected macrophages

    DOI: 10.1097/MD.0000000000022438

    PMID: 33080678

    		 Sample: Cell culture supernatant
  271. JOURNAL OF CLINICAL NEUROSCIENCE (2019) IF: 1.593
    Sex difference in IL-6 modulation of cognition among Chinese individuals with major depressive disorder

    DOI: 10.1016/j.jocn.2019.10.002

    PMID: 31629608

    		 Sample: Serum
  272. BMC Anesthesiology (2019) IF: 1.619
    A comparison of effects of scalp nerve block and local anesthetic infiltration on inflammatory response, hemodynamic response, and postoperative pain in patients undergoing craniotomy for cerebral aneurysms: a randomized controlled trial

    DOI: 10.1186/s12871-019-0760-4
    Sample: plasm
  273. Molecular Medicine Reports (2017) IF: 1.692
    Tetrahydroxy stilbene glucoside ameliorates H2O2-induced human brain microvascular endothelial cell dysfunction in vitro by inhibiting oxidative stress and inflammatory responses

    DOI: 10.3892/mmr.2017.7225
    Sample: Cell culture supernatant
  274. TRANSPLANT IMMUNOLOGY (2021) IF: 1.708
    miR-1287-5p upregulation inhibits the EMT and pro-inflammatory cytokines in LPS-induced human nasal epithelial cells (HNECs)

    DOI: 10.1016/j.trim.2021.101429

    PMID: 34139308

    		 Sample: HNECs cells
  275. Journal of Maternal-Fetal & Neonatal Medicine (2020) IF: 1.737
    Maternal omega-3 polyunsaturated fatty acids supplementation in pregnancy decreases MMP-1 levels in breastmilk: a cross-sectional study

    DOI: 10.1080/14767058.2020.1814241

    PMID: 32962453

    		 Sample: Milk
  276. Clinical Respiratory Journal (2023) IF: 1.761
    Assessment of incidence of cerebral vascular diseases and prediction of stroke risk in chronic obstructive pulmonary disease patients using multimodal biomarkers

    DOI: 10.1111/crj.13587
    Sample: serum
  277. Experimental and Therapeutic Medicine (2020) IF: 1.785
    Systematically transplanted human gingiva‑derived mesenchymal stem cells regulate lipid metabolism and inflammation in hyperlipidemic mice with periodontitis

    DOI: 10.3892/etm.2019.8256
    Sample: Serum
  278. Experimental and Therapeutic Medicine (2020) IF: 1.785
    Curcumin affects ox‑LDL‑induced IL‑6, TNF‑α, MCP‑1 secretion and cholesterol efflux in THP‑1 cells by suppressing the TLR4/NF‑κB/miR33a signaling pathway

    DOI: 10.3892/etm.2020.8915
    Sample: Cell culture supernatant
  279. Experimental and Therapeutic Medicine (2020) IF: 1.785
    Changes in expression of serum chemokine CXCL13 and IL-6 after hip replacement, and the relationship with lower limb vein thrombus

    DOI: 10.3892/etm.2019.8365

    PMID: 32104273

    		 Sample: Serum
  280. Experimental and Therapeutic Medicine (2020) IF: 1.785
    Application of dexmedetomidine-assisted intravertebral anesthesia in hip replacement and its influence on T-lymphocyte subsets

    DOI: 10.3892/etm.2020.8869
    Sample: serum
  281. LUNG (2020) IF: 1.817
    Are Serum Interleukin 6 and Surfactant Protein D Levels Associated with the Clinical Course of COVID-19?

    DOI: 10.1007/s00408-020-00393-8

    PMID: 32918573

    		 Sample: Plasma
  282. Molecular Medicine Reports (2019) IF: 1.851
    Chrysin protects human osteoarthritis chondrocytes by inhibiting inflammatory mediator expression via HMGB1 suppression

    DOI: 10.3892/mmr.2018.9724

    PMID: 30535473

    		 Sample: Cell culture medium
  283. European Journal of Obstetrics & Gynecology and Reproductive Biology (2020) IF: 1.868
    A comparative study of autologous rectus fascia pubovaginal sling surgery and synthetic transobturator vaginal tape procedure in treatment of women with urodynamic stress urinary incontinence

    DOI: 10.1016/j.ejogrb.2020.06.062
    Sample: blood
  284. MEDICINE (2019) IF: 1.87
    TLR4/NF-κB signaling pathway gene single nucleotide polymorphisms alter gene expression levels and affect ARDS occurrence and prognosis outcomes

    DOI: 10.1097/MD.0000000000016029
    Sample: plasma
  285. MEDICINE (2019) IF: 1.87
    A case-control study on the relationship between miRNAs single nucleotide polymorphisms and sepsis risk

    DOI: 10.1097/MD.0000000000016744
    Sample: Serum
  286. International Journal of Clinical and Experimental Pathology (2015) IF: 1.891
    An unusual case of iron deficiency anemia is associated with extremely low level of transferrin receptor

    PMID: 26339443

    		 Sample: serum
  287. MEDICAL SCIENCE MONITOR (2018) IF: 1.894
    Sinomenine Regulates Inflammatory Response and Oxidative Stress via Nuclear Factor kappa B (NF-κB) and NF-E2-Related Factor 2 (Nrf2) Signaling Pathways in Ankle Fractures in Children

    DOI: 10.12659/MSM.910740
    Sample: Serum
  288. MEDICAL SCIENCE MONITOR (2018) IF: 1.894
    Propofol Promotes Ankle Fracture Healing in Children by Inhibiting Inflammatory Response

    DOI: 10.12659/MSM.908592
    Sample: Serum
  289. PHLEBOLOGY (2020) IF: 1.914
    Study of association of varicose veins and inflammation by inflammatory markers:

    DOI: 10.1177/0268355520932410
    Sample: Plasma
  290. MEDICAL SCIENCE MONITOR (2020) IF: 1.918
    Avicularin Reduces the Expression of Mediators of Inflammation and Oxidative Stress in Bradykinin-Treated MG-63 Human Osteoblastic Osteosarcoma Cells

    DOI: 10.12659/MSM.921957

    PMID: 32463805

    		 Sample: Cell culture supernatant
  291. ARCHIVES OF ORAL BIOLOGY (2020) IF: 1.931
    Nec-1 attenuates inflammation and cytotoxicity induced by high glucose on THP-1 derived macrophages through RIP1

    DOI: 10.1016/j.archoralbio.2020.104858

    PMID: 32805637

    		 Sample: Cell culture supernatant
  292. Sport Sciences for Health (2022)
    The effects of aerobic exercise and sertraline on pro-inflammatory indices and amelioration of neurotrophic factors in patients who have undergone CABG

    DOI: 10.1007/s11332-022-00992-3
    Sample: plasma,serum
  293. International Journal of Inflammation (2022)
    The Association of Complements, TGF-β, and IL-6 with Disease Activity, Renal Damage, and Hematological Activity in Patients with Naïve SLE

    DOI: 10.1155/2022/7168935
    Sample: serum
  294. Medical Science Monitor Basic Research (2022)
    Production of Inflammatory Mediators in Conditioned Medium of Adipose Tissue-Derived Mesenchymal Stem Cells (ATMSC)-Treated Fresh Frozen Plasma

    DOI: 10.12659/MSMBR.933726
    Sample: Adipose Tissue-Derived Mesenchymal Stem Cells (ATM
  295. SCIENTIA PHARMACEUTICA (2022)
    Potential and Alternative Bioactive Compounds from Brown Agaricus bisporus Mushroom Extracts for Xerosis Treatment

    DOI: 10.3390/scipharm90040059
    Sample: HaCaT cells
  296. Sports (2023)
    Long-Term Resistance–Endurance Combined Training Reduces Pro-Inflammatory Cytokines in Young Adult Females with Obesity

    DOI: 10.3390/sports11030054
    Sample: serum
  297. Tuberkuloz ve Toraks-Tuberculosis and Thorax (2020)
    Evaluation of the relationship of serum vitamin D levels in COVID-19 patients with clinical course and prognosis.

    DOI: 10.5578/tt.70027
    Sample: blood
  298. Journal of Pediatric Infectious Diseases (2022) IF: 0.374
    Association between Interleukin-6 rs1800795 Polymorphism and Serum Interleukin-6 Levels and Full-Term Neonatal Sepsis

    DOI: 10.1055/s-0042-1757882
    Sample: serum
  299. Turkish Journal of Biochemistry-Turk Biyokimya Dergisi (2021) IF: 0.401
    The role of zonulin in the pathogenesis of diabetic retinopathy

    DOI: 10.1515/tjb-2020-0575
    Sample: serum
  300. Turkish Journal of Biochemistry-Turk Biyokimya Dergisi (2021) IF: 0.401
    Oxidative stress index can be a new marker related to disease severity in COVID-19

    DOI: 10.1515/tjb-2021-0013
    Sample: serum
  301. TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH (2022) IF: 0.533
    Clinical efficacy and inflammatory factors in knee osteoarthritis with glucosamine hydrochloride plus meloxicam

    DOI: 10.4314/tjpr.v21i3.30
    Sample: serum
  302. Revista da Associacao Medica Brasileira (2019) IF: 0.801
    TLR7 mediates increased vulnerability to ischemic acute kidney injury in diabetes

    DOI: 10.1590/1806-9282.65.8.1067

    PMID: 31531603

    		 Sample: Cell culture supernatant
  303. ACTA CLINICA BELGICA (2019) IF: 0.96
    Interleukin 8 as predictive factor for response to chemotherapy in colorectal cancer patients

    DOI: 10.1080/17843286.2019.1680133
    Sample: serum
  304. Journal of Huazhong University of Science and Technology-Medical Sciences (2017) IF: 0.964
    Applied value of monitoring serum hepcidin in differential diagnosis of infection versus tumor fevers

    DOI: 10.1007/s11596-017-1724-x
    Sample: Plasma
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