Current Position:Home>>Kits>>ELISA Kits>> Rat CASP3(Caspase 3) ELISA Kit

Rat CASP3(Caspase 3) ELISA Kit

Citations(83)Uniprot : P55213

Cat.No.:E-EL-R0160
Reactivity: Rat

Filter:

ELISA

To Purchase E-EL-R0160

Size:

96T
48T
24T
96T*5
96T*10

Price: $609

Qty:

Welcome to order from local distributors.

Protocols for ELISA

FAQ for ELISA

Have Questions?

Add to cart Bulk request

For research use only. Order now, ship in 3 days

Product Details

Properties

Assay type	Sandwich-ELISA
Format	96T/48T
Assay time	3.5h
Detection range	0.31-20 ng/mL
Sensitivity	0.19 ng/mL
Sample type &Sample volume	serum, plasma and other biological fluids; 100μL
Specificity	This kit recognizes Rat CASP3 in samples. No significant cross-reactivity or interference between Rat CASP3 and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are < 10%.
Application	This ELISA kit applies to the in vitro quantitative determination of Rat CASP3 concentrations in serum, plasma and other biological fluids.

Test Principle

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat CASP3. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Rat CASP3 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat CASP3, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Rat CASP3. You can calculate the concentration of Rat CASP3 in the samples by comparing the OD of the samples to the standard curve.

Kit components & Storage

An unopened kit can be stored at 2-8℃ for 1 month. If the kit is not supposed to be used within 1 month, store the components separately according to the following conditions once the kit is received.

Item	Specifications	Storage
Micro ELISA Plate(Dismountable)	96T: 8 wells ×12 strips 48T: 8 wells ×6 strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 48T: 1 vial, 60 μL
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 48T: 1 vial, 60 μL	-20℃(Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL
HRP Conjugate Diluent	1 vial, 14 mL
Concentrated Wash Buffer (25×)	1 vial, 30 mL
Substrate Reagent	1 vial, 10 mL	2-8℃(Protect from light)
Stop Solution	1 vial, 10 mL	2-8°C
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

Technical Data

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Rat CASP3 were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Rat CASP3 were tested on 3 different plates, 20 replicates in each plate.

	Intra-assay Precision			Inter-assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	20	20	20
Mean (ng/mL)	1.09	3.21	9.83	1.05	3.10	9.92
Standard deviation	0.07	0.14	0.54	0.06	0.12	0.49
CV (%)	6.42	4.36	5.49	5.71	3.87	4.94

Recovery

The recovery of Rat CASP3 spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type	Range (%)	Average Recovery (%)
Serum(n=8)	96-107	101
EDTA plasma (n=8)	87-102	93
Cell culture media (n=8)	91-101	96

Linearity

Samples were spiked with high concentrations of Rat CASP3 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

Target Information

Database Links	SwissProt: P55213
Synonyms	CPP32, CPP32B, SCA-1, Apoptain, Yama
Research Area	Cancer, Cell Biology, Metabolism, Neuroscience

Assay Procedures

	1. Add 100μL standard or sample to the wells. Incubate for 90 min at 37°C
	2. Discard the liquid, immediately add 100μL Biotinylated Detection Ab working solution to each well. Incubate for 60 min at 37°C
	3. Aspirate and wash the plate for 3 times
	4. Add 100μL HRP conjugate working solution. Incubate for 30 min at 37°C. Aspirate and wash the plate for 5 times
	5. Add 90μL Substrate Reagent. Incubate for 15 min at 37°C
	6. Add 50μL Stop Solution
	7. Read the plate at 450nm immediately. Calculation of the results

Related Products

Elabscience^® provides ancillary reagents required for ELISA kit developments.11 reagents in total, including reagents for coating, blocking, washing, improving the stability and reducing matrix interference etc.

Browse all ancillary reagents for ELISA kits

Other assay kits maybe meet your needs.

E-CK-A211	Annexin V-FITC/PI Apoptosis Kit
E-CK-A320	One-step TUNEL In Situ Apoptosis Kit (Green, FITC)
E-CK-A301	Mitochondrial Membrane Potential Assay Kit (with JC-1)
E-CK-A311

Citations

From now on, if you have published a paper by using any of our products since 1/1/2019, fill out the “Elabscience Publication Reward Application Form”carefully and send it to orders@elabscience.com, we will get back to you with the reward after we confirm it ASAP!

View more details about our Publication Reward >>

BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 7.419

Antioxidant and anti-apoptotic effects of tocotrienol-rich fraction against streptozotocin-induced diabetic retinopathy in rats

DOI: 10.1016/j.biopha.2022.113533
PMID: 36076612	Sample: retinal

BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 6.53

Glutamine prevents upregulation of NF-kB signaling and caspase 3 activation in ischaemia/reperfusion-induced testicular damage: An animal model

DOI: 10.1016/j.biopha.2022.113056
PMID: 35658227	Sample: testicular tissue

LIFE SCIENCES (2022) IF: 5.037

Integration of synthetic and natural derivatives revives the therapeutic potential of temozolomide against glioma- an in vitro and in vivo perspective

DOI: 10.1016/j.lfs.2022.120609
PMID: 35526592	Sample: C6 cell,U-87 MG cell,LN229 cell

CHEMOSPHERE (2019) IF: 5.108

Impact of binary waterborne mixtures of nickel and zinc on hypothalamic-pituitary-testicular axis in rats

DOI: 10.1016/j.chemosphere.2019.124501
PMID: 31398612	Sample: Serum

CHEMICO-BIOLOGICAL INTERACTIONS (2023) IF: 5.168

Protective effect of eicosapentaenoic acid against estradiol valerate-induced endometrial hyperplasia via modulation of NF-κB/HIF-1α/VEGF signaling pathway in rats

DOI: 10.1016/j.cbi.2023.110399
	Sample: uterine tissue

CHEMICO-BIOLOGICAL INTERACTIONS (2021) IF: 5.194

Plumbagin induces testicular damage via mitochondrial-dependent cell death

DOI: 10.1016/j.cbi.2021.109582
PMID: 34302802	Sample: testis

Pharmaceuticals (2022) IF: 5.215

Lycopene Modulates Oxidative Stress and Inflammation in Hypercholesterolemic Rats

DOI: 10.3390/ph15111420
	Sample: Cardiac,Renal

FOOD AND CHEMICAL TOXICOLOGY (2022) IF: 5.572

Banana peel ameliorated hepato-renal damage and exerted anti-inflammatory and anti-apoptotic effects in metal mixture mediated hepatic nephropathy by activation of Nrf2/ Hmox-1 and inhibition of Nfkb pathway

DOI: 10.1016/j.fct.2022.113471
PMID: 36270409	Sample: liver,kidney

REDOX REPORT (2022) IF: 5.696

Atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion injury

DOI: 10.1080/13510002.2022.2129192
PMID: 36200598	Sample: ovarian

ENVIRONMENTAL POLLUTION (2019) IF: 5.714

Selenium abates reproductive dysfunction via attenuation of biometal accumulation, oxido-inflammatory stress and caspase-3 activation in male rats exposed to arsenic

DOI: 10.1016/j.envpol.2019.113079
PMID: 31473390	Sample: Serum

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2022) IF: 5.785

Influence of furan and lead co-exposure at environmentally relevant concentrations on neurobehavioral performance, redox-regulatory system and apoptotic responses in rats

DOI: 10.1016/j.etap.2022.104011
	Sample: cerebellum,cerebrum

Frontiers in Pharmacology (2021) IF: 5.811

Therapeutic Potentials of Selected Antihypertensive Agents and Their Fixed-Dose Combinations Against Trastuzumab-Mediated Cardiotoxicity

DOI: 10.3389/fphar.2020.610331
	Sample: Cardiac tissue

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021) IF: 5.924

Escitalopram Targets Oxidative Stress, Caspase-3, BDNF and MeCP2 in the Hippocampus and Frontal Cortex of a Rat Model of Depression Induced by Chronic Unpredictable Mild Stress

DOI: 10.3390/ijms22147483
PMID: 34299103	Sample: Hippocampus

Mycotoxin Research (2023) IF: 4.082

Neurobehavioral and biochemical responses to artemisinin-based drug and aflatoxin B1 co-exposure in rats

DOI: 10.1007/s12550-023-00474-6
	Sample: cerebellar,cerebral

PHYTOTHERAPY RESEARCH (2020) IF: 4.087

Lavender and coriander essential oils and their main component linalool exert a protective effect against amyloid‐β neurotoxicity

DOI: 10.1002/ptr.6827
	Sample: Cell lysate

TOXICOLOGY (2020) IF: 4.099

Protocatechuic acid modulates reproductive dysfunction linked to furan exposure in rats

DOI: 10.1016/j.tox.2020.152556
PMID: 32758512	Sample: Serum,Tissue homogenate

ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119

Platelet-rich plasma exhibits anti-inflammatory effect and attenuates cardiomyocyte damage by reducing NF-κB and enhancing VEGF expression in isoproterenol induced cardiotoxicity model

DOI: 10.1002/tox.23456
PMID: 35014750	Sample: cardiac tissue

SAUDI JOURNAL OF BIOLOGICAL SCIENCES (2021) IF: 4.219

Neuroprotective efficacy of 4-Hydroxyisoleucine in experimentally induced intracerebral hemorrhage

DOI: 10.1016/j.sjbs.2021.07.010
PMID: 34764759	Sample: brain

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2022) IF: 4.223

3-Indolepropionic acid prevented chlorpyrifos-induced hepatorenal toxicities in rats by improving anti-inflammatory, antioxidant, and pro-apoptotic responses and abating DNA damage

DOI: 10.1007/s11356-022-21075-3
PMID: 35644820	Sample: Hepatic,renal

NEUROTOXICOLOGY (2021) IF: 4.294

The diuretic amiloride attenuates doxorubicin-induced chemobrain in rats: Behavioral and mechanistic study

DOI: 10.1016/j.neuro.2021.10.002
PMID: 34656704	Sample: hippocampus

REDOX REPORT (2022) IF: 4.412

Suppression of glutathione system and upregulation of caspase 3-dependent apoptosis mediate rohypnol-induced gastric injury

DOI: 10.1080/13510002.2022.2074128
PMID: 35535549	Sample: gastric tissue

MOLECULES (2022) IF: 4.412

Guggulsterone Mediated JAK/STAT and PPAR-Gamma Modulation Prevents Neurobehavioral and Neurochemical Abnormalities in Propionic Acid-Induced Experimental Model of Autism

DOI: 10.3390/molecules27030889
	Sample: brain,blood plasma

Toxics (2022) IF: 4.472

Quercetin-3-O-β-D-Glucopyranoside-Rich Fraction from Spondias mombin Leaves Halted Responses from Oxidative Stress, Neuroinflammation, Apoptosis, and Lipid Peroxidation in the Brain of Dichlorvos-Treated Wistar Rats.

DOI: 10.3390/toxics10080477
	Sample: brain

INFLAMMOPHARMACOLOGY (2021) IF: 4.473

Neuroprotective effects of roflumilast against quinolinic acid-induced rat model of Huntington’s disease through inhibition of NF-κB mediated neuroinflammatory markers and activation of cAMP/CREB/BDNF signaling pathway

DOI: 10.1007/s10787-020-00787-3
	Sample: Tissue homogenate(brain)

PSYCHOPHARMACOLOGY (2021) IF: 4.53

Selenium abates manganese–induced striatal and hippocampal toxicity via abrogation of neurobehavioral deficits, biometal accumulation, oxidative stress, inflammation, and caspase-3 activation in rats

DOI: 10.1007/s00213-021-06010-7
	Sample: striatum,hippocampus

PSYCHOPHARMACOLOGY (2021) IF: 4.53

Effects of catechin on a rodent model of autism spectrum disorder: implications for the role of nitric oxide in neuroinflammatory pathway

DOI: 10.1007/s00213-021-05941-5
PMID: 34448020	Sample: brain

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2021) IF: 4.86

Indole-3-propionic acid mitigates chlorpyrifos-mediated neurotoxicity by modulating cholinergic and redox-regulatory systems, inflammatory stress, apoptotic responses and DNA damage in rats

DOI: 10.1016/j.etap.2021.103786
PMID: 34915193	Sample: brain

MOLECULES (2022) IF: 4.927

Restoration of Hepatic and Intestinal Integrity by Phyllanthus amarus Is Dependent on Bax/Caspase 3 Modulation in Intestinal Ischemia-/Reperfusion-Induced Injury

DOI: 10.3390/molecules27165073
PMID: 36014309	Sample: intestinal,hepatic

MOLECULES (2022) IF: 4.927

7-Hydroxyflavone Alleviates Myocardial Ischemia/Reperfusion Injury in Rats by Regulating Inflammation

DOI: 10.3390/molecules27175371
PMID: 36080137	Sample: serum

TOXICON (2022) IF: 3.033

Caffeic acid protects against DNA damage, oxidative and inflammatory mediated toxicities, and upregulated caspases activation in the hepatorenal system of rats treated with aflatoxin B1

DOI: 10.1016/j.toxicon.2021.12.021
PMID: 34995555	Sample: liver,kidney

TOXICON (2022) IF: 3.035

Co-exposure to aflatoxin B1 and therapeutic coartem worsens hepatic and renal function through enhanced oxido-inflammatory responses and apoptosis in rats

DOI: 10.1016/j.toxicon.2022.106988
	Sample: liver，kidney

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2019) IF: 3.061

Neurobehavioural and biochemical responses associated with exposure to binary waterborne mixtures of zinc and nickel in rats

DOI: 10.1016/j.etap.2019.103294
	Sample: cerebellum,cerebrum,liver

CHEMICO-BIOLOGICAL INTERACTIONS (2017) IF: 3.143

Protective properties of 6-gingerol-rich fraction from Zingiber officinale (Ginger) on chlorpyrifos-induced oxidative damage and inflammation in the brain, ovary and uterus of rats

DOI: 10.1016/j.cbi.2017.03.017
	Sample: Tissue homogenate

REPRODUCTIVE TOXICOLOGY (2022) IF: 3.143

Codeine alters female reproductive function by targeting ovarian steroidogenesis and folliculogenesis via the induction of oxidative stress, inflammation, and apoptosis

DOI: 10.1016/j.reprotox.2022.02.001
PMID: 35158039	Sample: Ovarian

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2022) IF: 3.148

Neuroprotection by Trans-Resveratrol in Rats With Intracerebral Hemorrhage: Insights into the Role of Adenosine A1 Receptors

DOI: 10.1093/jnen/nlac047
PMID: 35799401	Sample: brain

EUROPEAN JOURNAL OF PHARMACOLOGY (2019) IF: 3.17

Dietary protocatechuic acid abrogates male reproductive dysfunction in streptozotocin-induced diabetic rats via suppression of oxidative damage, inflammation and caspase-3 activity

DOI: 10.1016/j.ejphar.2019.01.033
PMID: 30690002	Sample: Tissue homogenate

Cardiovascular Toxicology (2021) IF: 3.239

Wnt/β-Catenin Antagonist Pyrvinium Exerts Cardioprotective Effects in Polymicrobial Sepsis Model by Attenuating Calcium Dyshomeostasis and Mitochondrial Dysfunction

DOI: 10.1007/s12012-021-09643-4
PMID: 33723718	Sample: Tissue homogenate(Cardiac)

Cardiovascular Toxicology (2022) IF: 3.239

Upregulation of Uric Acid Production and Caspase 3 Signalling Mediates Rohypnol-Induced Cardiorenal Damage

DOI: 10.1007/s12012-022-09723-z
PMID: 35103933	Sample: cardiac,renal

HUMAN & EXPERIMENTAL TOXICOLOGY (2023) IF: 3.247

The IL-6/HO-1/STAT3 signaling pathway is implicated in the amelioration of acetaminophen-induced hepatic toxicity: A neonatal rat model

DOI: 10.1177/09603271231151376
	Sample: hepatic

NEUROTOXICOLOGY (2019) IF: 3.263

Neuroprotective mechanisms of selenium against arsenic-induced behavioral impairments in rats

DOI: 10.1016/j.neuro.2019.10.009
PMID: 31678059	Sample: Tissue homogenate

TOXICOLOGY AND APPLIED PHARMACOLOGY (2020) IF: 3.347

Co-administration of Luteolin mitigated toxicity in rats' lungs associated with doxorubicin treatment

DOI: 10.1016/j.taap.2020.115380
PMID: 33358696	Sample: Tissue homogenate

INTERNATIONAL IMMUNOPHARMACOLOGY (2019) IF: 3.361

The ameliorating effect of cannabinoid type 2 receptor activation on brain, lung, liver and heart damage in cecal ligation and puncture-induced sepsis model in rats

DOI: 10.1016/j.intimp.2019.105978
PMID: 31767546	Sample: Tissue homogenate

LIFE SCIENCES (2019) IF: 3.448

Safranal, a constituent of saffron, exerts gastro-protective effects against indomethacin-induced gastric ulcer

DOI: 10.1016/j.lfs.2019.03.054
PMID: 30914317	Sample: Tissue homogenate

BIOMEDICINE & PHARMACOTHERAPY (2018) IF: 3.457

The effects of safranal, a constitute of saffron, and metformin on spatial learning and memory impairments in type-1 diabetic rats: behavioral and hippocampal histopathological and biochemical evaluations

DOI: 10.1016/j.biopha.2018.07.165
PMID: 30092399	Sample: Tissue homogenate

BIOMEDICINE & PHARMACOTHERAPY (2018) IF: 3.457

Protective effects of L-theanine against doxorubicin-induced nephrotoxicity in rats

DOI: 10.1016/j.biopha.2018.09.171
	Sample: plasma,renal tissues

ACS Omega (2022) IF: 3.512

Myricetin (3,3′,4′,5,5′,7-Hexahydroxyflavone) Prevents 5-Fluorouracil-Induced Cardiotoxicity

DOI: 10.1021/acsomega.1c06475
	Sample: cardiac tissue

Toxicology Research (2021) IF: 3.524

Chlorogenic acid abates oxido-inflammatory and apoptotic responses in the liver and kidney of Tamoxifen-treated rats

DOI: 10.1093/toxres/tfab002
	Sample: hepatic,renal

METABOLIC BRAIN DISEASE (2021) IF: 3.584

Guggulsterone ameliorates ethidium bromide-induced experimental model of multiple sclerosis via restoration of behavioral, molecular, neurochemical and morphological alterations in rat brain

DOI: 10.1007/s11011-021-00691-x
PMID: 33635478	Sample: Tissue homogenate(brain)

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2020) IF: 3.606

Neuroprotective role of gallic acid in aflatoxin B1‐induced behavioral abnormalities in rats

DOI: 10.1002/jbt.22684
	Sample: cerebrum tissue lysate supernatant

LIFE SCIENCES (2020) IF: 3.647

l-theanine alleviates liver and kidney dysfunction in septic rats induced by cecal ligation and puncture

DOI: 10.1016/j.lfs.2020.117502
PMID: 32142764	Sample: Tissue homogenate

LIFE SCIENCES (2020) IF: 3.647

Downregulation of redox imbalance and iNOS/NF-ĸB/caspase-3 signalling with zinc supplementation prevents urotoxicity of cyclophosphamide-induced hemorrhagic cystitis in rats

DOI: 10.1016/j.lfs.2020.118913
PMID: 33333050	Sample: Bladder

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2021) IF: 3.652

Biochemical and histological alterations of doxorubicin-induced neurotoxicity in rats: Protective role of luteolin

DOI: 10.1002/jbt.22962
PMID: 34766659	Sample: brain

JOURNAL OF FOOD BIOCHEMISTRY (2022) IF: 3.654

Twelve weeks of treadmill exercise training with green tea extract reduces myocardial oxidative stress and alleviates cardiomyocyte apoptosis in aging rat: The emerging role of BNIP3 and HIF-1α/IGFBP3 pathway

DOI: 10.1111/jfbc.14397
PMID: 36069470	Sample: heart tissue

METABOLIC BRAIN DISEASE (2022) IF: 3.655

Sarcococca saligna ameliorated D-galactose induced neurodegeneration through repression of neurodegenerative and oxidative stress biomarkers

DOI: 10.1007/s11011-022-01046-w
PMID: 35881299	Sample: Brain tissue

BMC Complementary and Alternative Medicine (2021) IF: 3.659

Effect of the standard herbal preparation, STW5, treatment on dysbiosis induced by dextran sodium sulfate in experimental colitis

DOI: 10.1186/s12906-021-03337-8
PMID: 34103031	Sample: colon

NEUROSCIENCE (2023) IF: 3.708

Essential Trace Elements Prevent the Impairment in the Retention Memory, Cerebral Cortex, and Cerebellum Damage in Male Rats Exposed to Quaternary Metal Mixture by Up-regulation, of Heme Oxygynase-1 and Down-regulation of Nuclear Factor Erythroid 2-relate

DOI: 10.1016/j.neuroscience.2023.01.002
PMID: 36646412	Sample: cerebral cortex,cerebellum

BIOLOGICAL TRACE ELEMENT RESEARCH (2021) IF: 3.738

Conivaptan and Boric Acid Treatments in Acute Kidney Injury: Is This Combination Effective and Safe?

DOI: 10.1007/s12011-021-02977-8
PMID: 34676519	Sample: serum

Heliyon (2020) IF: 3.776

In vivo exposure to codeine induces reproductive toxicity: role of HER2 and p53/Bcl-2 signaling pathway

DOI: 10.1016/j.heliyon.2020.e05589
	Sample: testicular

JOURNAL OF KING SAUD UNIVERSITY SCIENCE (2020) IF: 3.819

The protecting role of Moringa oleifera in cypermethrin-induced mitochondrial dysfunction and apoptotic events in rats brain

DOI: 10.1016/j.jksus.2020.06.006
	Sample: Tissue homogenate

FOOD AND CHEMICAL TOXICOLOGY (2018) IF: 3.977

Protocatechuic acid ameliorates neurobehavioral deficits via suppression of oxidative damage, inflammation, caspase-3 and acetylcholinesterase activities in diabetic rats

DOI: 10.1016/j.fct.2018.12.040
PMID: 30597223	Sample: Tissue homogenate

NEUROTOXICITY RESEARCH (2023) IF: 3.978

Restraint Stress Exacerbates Apoptosis in a 6-OHDA Animal Model of Parkinson Disease

DOI: 10.1007/s12640-022-00630-3
	Sample: striatal tissue

NEUROSCIENCE LETTERS (2018) IF: 2.159

Rutin attenuates neurobehavioral deficits, oxidative stress, neuro-inflammation and apoptosis in fluoride treated rats

DOI: 10.1016/j.neulet.2018.06.023
	Sample: Tissue homogenate

HUMAN & EXPERIMENTAL TOXICOLOGY (2019) IF: 2.171

Hepatorenal protective effects of protocatechuic acid in rats administered with anticancer drug methotrexate:

DOI: 10.1177/0960327119871095
	Sample: hepatic and renal

TOXICOLOGY MECHANISMS AND METHODS (2019) IF: 2.276

Zinc abrogates anticancer drug tamoxifen-induced hepatotoxicity by suppressing redox imbalance, NO/iNOS/NF-ĸB signaling, and caspase-3-dependent apoptosis in female rats

DOI: 10.1080/15376516.2019.1669243
	Sample: liver

TOXICOLOGY MECHANISMS AND METHODS (2020) IF: 2.295

Comparative effects of galactose-induced aging on mitochondrial permeability transition in rat liver and testis

DOI: 10.1080/15376516.2020.1755921
	Sample: liver

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2017) IF: 2.341

SIRT1 exerts neuroprotective effects by attenuating cerebral ischemia/reperfusion-induced injury via targeting p53/microRNA-22

DOI: 10.3892/ijmm.2016.2806
	Sample: Tissue homogenate

Metabolic Syndrome and Related Disorders (2022) IF: 2.363

Naringenin Prevents Inflammation, Apoptosis, and DNA Damage in Potassium Oxonate-Induced Hyperuricemia in Rat Liver Tissue: Roles of Cytochrome C, NF-κB, Caspase-3, and 8-Hydroxydeoxyguanosine

DOI: 10.1089/met.2022.0028
PMID: 35796694	Sample: Liver tissue

BMC Pharmacology & Toxicology (2022) IF: 2.605

Accidental lead in contaminated pipe-borne water and dietary furan intake perturbs rats’ hepatorenal function altering oxidative, inflammatory, and apoptotic balance

DOI: 10.1186/s40360-022-00615-0
	Sample: hepatic,renal

CHEMICO-BIOLOGICAL INTERACTIONS (2016) IF: 2.618

Chemoprotective role of quercetin in manganese-induced toxicity along the brain-pituitary-testicular axis in rats

DOI: 10.1016/j.cbi.2016.12.019
	Sample: Tissue homogenate

JOURNAL OF FOOD BIOCHEMISTRY (2021) IF: 2.72

Chlorogenic acid co-administration abates tamoxifen-mediated reproductive toxicities in male rats: An experimental approach

DOI: 10.1111/jfbc.13615
PMID: 33491243	Sample: Tissue homogenate

FUNDAMENTAL & CLINICAL PHARMACOLOGY (2022) IF: 2.747

The protective effect of 3-indolepropanoic acid on aflatoxin B1-induced systemic perturbation of the liver and kidney function in rats

DOI: 10.1111/fcp.12842
PMID: 36214208	Sample: liver,kidney

FUNDAMENTAL & CLINICAL PHARMACOLOGY (2021) IF: 2.748

Roflumilast improves resolution of sepsis-induced acute kidney injury by retarding late phase renal interstitial immune cells infiltration and leakage in urinary sediments

DOI: 10.1111/fcp.12711
PMID: 34212425	Sample: renal

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2019) IF: 2.773

Co-treatment of piracetam with risperidone rescued extinction deficits in experimental paradigms of post-traumatic stress disorder by restoring the physiological alterations in cortex and hippocampus

DOI: 10.1016/j.pbb.2019.172763
	Sample: plasma

HUMAN & EXPERIMENTAL TOXICOLOGY (2021) IF: 2.903

Luteolin attenuates doxorubicin-induced derangements of liver and kidney by reducing oxidative and inflammatory stress to suppress apoptosis:

DOI: 10.1177/09603271211006171
	Sample: Tissue homogenate

NEUROSCIENCE RESEARCH (2023) IF: 2.904

Neuroprotection by trans-resveratrol in rats with N-methyl-D-aspartate (NMDA)–induced retinal injury: insights into the role of adenosine A1 receptors

DOI: 10.1016/j.neures.2023.02.004
	Sample: retinal

Molecular Medicine Reports (2016) IF: 2.952

Astaxanthin reduces type 2 diabetic‑associated cognitive decline in rats via activation of PI3K/Akt and attenuation of oxidative stress

DOI: 10.3892/mmr.2015.4615
	Sample: Tissue homogenate

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2019) IF: 2.965

Fluoride and diethylnitrosamine coexposure enhances oxido‐inflammatory responses and caspase‐3 activation in liver and kidney of adult rats

DOI: 10.1002/jbt.22327
	Sample: Serum

Veterinary Research Forum (2019) IF: 1.054

Crocin exerts improving effects on indomethacin-induced small intestinal ulcer by antioxidant, anti-inflammatory and anti-apoptotic mechanisms

DOI: 10.30466/vrf.2018.93512.2256
	Sample: Small intestine tissue

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2017) IF: 1.822

Taurine reverses sodium fluoride-mediated increase in inflammation, caspase-3 activity, and oxidative damage along the brain–pituitary–gonadal axis in male rats

DOI: 10.1139/cjpp-2016-0641
	Sample: Tissue homogenate

DRUG AND CHEMICAL TOXICOLOGY (2019) IF: 1.946

Behavioral, histopathological, and biochemical evaluations on the effects of cinnamaldehyde, naloxone, and their combination in morphine-induced cerebellar toxicity

DOI: 10.1080/01480545.2019.1681446
PMID: 31656103	Sample: Tissue homogenate

Current Research in Toxicology (2022)

Zn and Se abrogate heavy metal mixture induced ovarian and thyroid oxido-inflammatory effects mediated by activation of NRF2-HMOX-1 in female albino rats

DOI: 10.1016/j.crtox.2022.100098
	Sample: ovarian,thyroid,thyroid cell

Toxicology Reports (2019)

Manganese suppresses oxidative stress, inflammation and caspase-3 activation in rats exposed to chlorpyrifos

DOI: 10.1016/j.toxrep.2019.02.007
PMID: 30859069	Sample: Tissue homogenate

Turkish Journal of Biochemistry-Turk Biyokimya Dergisi (2020) IF: 0.373

Effects of mesenchymal stem cell and amnion membrane transfer on prevention of pericardial adhesions

DOI: 10.1515/tjb-2019-0309
	Sample: serum

Show AllShorten

Reviews/Q&A

Show all
Reviews
Q&A

... Show All Show Less

*Product Name:
*Catalog Number:
Size:
*Name:
*Email:
*Phone:
*Message:
*Country:
*When will you use it?	Within 1 month In 2 to 3 month In 4 to 6 month 6 months later
*Captcha:	Click to load Captcha