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100Tests $ 57.00
50Tests $ 32.00
100Tests×2 $ 86.00
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For research use only.

Alternate Names CD8A,  MAL,  T-cell surface glycoprotein CD8 alpha chain,  T-lymphocyte differentiation antigen T8/Leu-2
Clone No
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Background CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Abbre CD8a
Swissprot
Host Rat
Reactivity Mouse
Clonality Monoclonal
Isotype Rat IgG2a, κ
Isotype Control E-AB-F09832L
Applications
FCM
Cellular Localization
Membrane
Form Liquid
Concentration
5 μL/Test
Conjugation Elab Fluor®488
Conjugation Information Elab Fluor® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date 12 months
Shipping Ice bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Other Clones

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Other Formats

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APC

Biotin

Elab Fluor®488

Elab Fluor®647

Elab Fluor®700

Elab Fluor®Red 780

Elab Fluor®Violet 450

Elab Fluor®Violet 500

Elab Fluor®Violet 540

FITC

None (AF/LE)

PE

PE/Cyanine 5.5

PE/Cyanine 7

PE/Elab Fluor®594

PerCP

PerCP/Cyanine 5.5

Unconjugated

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