Purified Anti-Human CD276 Antibody[6A1] (AN004110P)

For research use only.
Alternate Names | B7H, UNQ, PRO, B7-H, B7RP, B7 homolog, B7H34Ig-B7-H, PSEC, 4Ig-B7-H, CD276, 4Ig-B7-H3, B7-H3, B7H3, B7RP-2, B7 homolog 3, B7H34Ig-B7-H3, CD276 antigen, CD276 molecule, Costimulatory molecule, PSEC0249, UNQ309, PRO352, B7RP-2, 4Ig-B7-H3, B7H3, B7-H3, CD276 antigen |
Clone No | |
Leadtime | Inquire |
Verified Samples | Verified Samples in FCM: PC-3 |
Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
Background | The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Recombinant Human CD276 protein |
Abbre | CD276 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Purification Method | >98%, Protein A/G purified |
Isotype | Mouse IgG1, κ |
Applications |
FCM
|
Research Areas | Immunology;Cancer;Stem Cells |
Concentration |
≥ 1 mg/mL
|
Conjugation | Unconjugated |
Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12 months |
Shipping | Ice bag |
Other Clones
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Unconjugated
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