QuicKey Pro Human HTRA1 (HtrA Serine Peptidase 1) ELISA Kit (E-OSEL-H0074)
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For research use only.
Product Summary
Get more sensitive and precise results with saving at least 1-2h comparing to traditional ELISA Kits. The new developed technology in house will help to accelerate your science research in a more efficient way.
| Sensitivity | 0.19 ng/mL |
| Detection Range | 0.31-20 ng/mL |
| Sample Volume | 50 μL |
| Total Assay Time | 1 h 30 min |
| Reactivity | Human |
| Specificity | This kit recognizes Human HTRA1 in samples. No significant cross-reactivity or interference between Human HTRA1 and analogues was observed. |
| Recovery | 80%-120% |
| Sample Type | Serum, plasma and other biological fluids |
| Detection Method | Colorimetric method, ELISA, Sandwich |
| Assay Type | Sandwich-ELISA |
| Size | 96T / 48T / 24T / 96T*5 / 96T*10 |
| Storage | 2-8℃ |
| Expiration Date | 6 months |
Background
HtrA Serine Peptidase 1 (HTRA1) is a serine protease and belongs to the trypsin family. The HTRA1 protein is composed of 480 amino acids and has serine protease activity. It can target various proteins, such as fibronectin and other extracellular matrix proteins, and play a role in extracellular matrix remodeling. Mutations in the HTRA1 gene are associated with autosomal recessive hereditary cerebral arteropathy (CARASIL) accompanied by subcortical infarction and leukoencephalopathy. HTRA1 may play an important role in the process of apoptosis. Its abnormal expression or changes in activity may be related to the occurrence and development of various diseases, such as neurodegenerative diseases and cardiovascular diseases. As a potential drug target, it provides new research directions for the treatment of related diseases, such as the development of inhibitors or regulators targeting HTRA1, etc.
| Gene Alias | HTRA1 |
| Gene ID | 5654 |
| Uniport ID | Q92743 |
| Protein Alias | HTRA1 |
| Research Area | Stem Cells , Cardiovascular , Cancer , Neuroscience |
| Cat.No. | Product Name | Clone No. |
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