QuicKey Pro Human RNASE3 (Ribonuclease A3/Eosinophil Cationic Protein) ELISA Kit (E-OSEL-H0078)
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For research use only.
Product Summary
Get more sensitive and precise results with saving at least 1-2h comparing to traditional ELISA Kits. The new developed technology in house will help to accelerate your science research in a more efficient way.
| Sensitivity | 23.44 pg/mL |
| Detection Range | 39.06-2500 pg/mL |
| Sample Volume | 50 μL |
| Total Assay Time | 1 h 30 min |
| Reactivity | Human |
| Specificity | This kit recognizes Human RNASE3 in samples. No significant cross-reactivity or interference between Human RNASE3 and analogues was observed. |
| Recovery | 80%-120% |
| Sample Type | Serum, plasma and other biological fluids |
| Detection Method | Colorimetric method, ELISA, Sandwich |
| Assay Type | Sandwich-ELISA |
| Size | 96T / 48T / 24T / 96T*5 / 96T*10 |
| Storage | 2-8℃ |
| Expiration Date | 6 months |
Background
ECP (eosinophil cationic protein), also known as RNS3 or RNASE3 (ribonuclease, RNase A family), is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family. ECP localizes to the granule matrix of the eosinophil and is involved in the immune response system. ECP is a cytotoxin, neurotoxin and helminthotoxin that is secreted by activated human eosinophils. ECP exhibits anti-parasitic, antibacterial and ribonucleolytic activities. It has been suggested that ECP induces the neurotoxic effect known as the Gordon phenomenon, a syndrome manifested by ataxia, muscular rigidity, paralysis and tremor that may lead to death. ECP is considered a marker of eosinophilic inflammation and high levels have been found in cases of active asthma and other allergic diseases.
| Gene Alias | RNASE3 |
| Gene ID | 6037 |
| Uniport ID | P12724 |
| Protein Alias | RNASE3 |
| Research Area | Immunology |
| Cat.No. | Product Name | Clone No. |
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