Purified Anti-Mouse CD86 Antibody[GL-1] (E-AB-F0994A)
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For research use only.
Conjugation: Unconjugated
APC Biotin Elab Bright™Violet 421 Elab Bright™Violet 510 Elab Bright™Violet 650 Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 Elab Fluor®Violet 610 FITC None (AF/LE) PE PE/Cyanine 5.5 PE/Cyanine 7 PE/Elab Fluor®594 Unconjugated Show More
| Alternate Names | sCD86, CLS, ETC, T-lymphocyte activation antigen CD, Early T-cell costimulatory molecule, TS/A, Cd28l, Activation B7-2 antigen, B7, B7.2, B70, B7-2, Cd28l2, CLS1, Early T-cell costimulatory molecule 1, ETC-1, Ly58, Ly-58, MB7, MB7-2, T-lymphocyte activation antigen CD86, TS/A-2, Cd86, B7-2, Ly-58 |
| Clone | |
| Leadtime | Order now, ship in 3 days |
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Mouse CD86 gene |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Background | CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
| Immunogen | Recombinant Mouse CD86 protein |
| Abbre | CD86 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Rat IgG2a, κ |
| Isotype Control | Purified Rat IgG2a, κ Isotype Control[2A3] |
| Applications |
FCM
|
| Research Areas | Cell Biology;Costimulatory Molecules;Immunology;Neuroscience;Neuroscience Cell Markers |
| Cellular Localization |
Cell membrane, Secreted
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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