Name: PE Anti-Human HLA-DQ Antibody[1a3]
Brand: Elabscience
SKU: AN00421D
Price: 66.0 USD
Availability: InStock

Isotype	Mouse IgG2a, κ
Host	Mouse
Reactivity	Human
Applications	FCM
Clonality	Monoclonal
Abbre	HLA-DQ
Synonyms	MHC class II DQ monomorphic antigen, MHC II
Swissprot	P01906
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Clone No.	1a3
Conjugation	PE
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	HLA-DQ is also known as MHC class II DQ monomorphic antigen. The major histocompatibility complex is composed of two heterodimeric glycoproteins (α and β chains) with apparent molecular weights of 27 and 32 kD. In contrast to other MHC class II molecules, both polypeptide chains of HLA-DQ are polymorphic, with the α chain showing an extremely high degree of polymorphism. HLA-DQ is expressed on B cells in the peripheral blood, and weakly expressed on activated T cells and some monocytes. HLA-DQ is absent on hematopoietic progenitors, resting T cells, erythrocytes, and platelets. HLA-DQ is expressed after HLA-DR and HLA-DP in hematopoietic development. HLA-DQ presents peptide fragments mainly from degraded intravesicular and extracellular proteins to CD4+ T lymphocytes. Specific alleles of HLA-DQ have been linked to the pathogenesis of several autoimmune diseases (including diabetes), both as a susceptibility and resistance factor depending on the particular polymorphism.

Cat.No.	Product Name	Sizes
E-CK-A105	10×ACK Lysis Buffer	500mL , 200mL , 100mL
E-CK-A107	Cell Staining Buffer	500mL , 200mL , 100mL

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1a3

Size	Price	Qty
100Tests	$ 228.00	- +
20Tests	$ 66.00	- +
100Tests×2	$ 342.00	- +

PE Anti-Human HLA-DQ Antibody[1a3] (AN00421D)