Elab Fluor® 700 Anti-Mouse CD8a Antibody[53-6.7] (E-AB-F1104M1)
For research use only.
Conjugation: Elab Fluor®700
APC Biotin Elab Bright™Violet 421 Elab Bright™Violet 510 Elab Bright™Violet 650 Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 Elab Fluor®Red 780 Elab Fluor®Violet 450 Elab Fluor®Violet 500 Elab Fluor®Violet 540 FITC None (AF/LE) PE PE/Cyanine 5.5 PE/Cyanine 7 PE/Elab Fluor®594 PerCP PerCP/Cyanine 5.5 Unconjugated Show More
| Isotype | Rat IgG2a, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | CD8a |
| Synonyms | CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2 |
| Swissprot | |
| Cellular Localization | Membrane |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Clone No. | 53-6.7 |
| Conjugation | Elab Fluor®700 |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. |
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