ADRA1B Polyclonal Antibody

Uniprot : P35368
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30575

      Synonyms:ADA1B,ADRA 1,Adra 1b,ADRA1,ADRA1B,Adrenergic alpha 1B receptor,Adrenergic receptor alpha 1b,Adrenoceptor alpha 1B,Alpha 1 adrenergic receptor,Alpha 1B adrenoceptor,Alpha 1B adrenoreceptor,Alpha-1B adrenergic receptor,Alpha-1B adrenoceptor,Alpha-1B adrenoreceptor,Alpha1 adrenergic receptor,Alpha1B adrenergic receptor,Alpha1BAR

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IF,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms ADA1B,ADRA 1,Adra 1b,ADRA1,ADRA1B,Adrenergic alpha 1B receptor,Adrenergic receptor alpha 1b,Adrenoceptor alpha 1B,Alpha 1 adrenergic receptor,Alpha 1B adrenoceptor,Alpha 1B adrenoreceptor,Alpha-1B adrenergic receptor,Alpha-1B adrenoceptor,Alpha-1B adrenoreceptor,Alpha1 adrenergic receptor,Alpha1B adrenergic receptor,Alpha1BAR
      Swissprot P35368
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from the C-terminal region of human AR-α1B
      Application WB(Detection kit: E-IR-R304),IF,ELISA
      Recommended dilution WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus membrane. Cell membrane. Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.

      Images

      Western Blot analysis of Jurkat cells with ADRA1B Polyclonal Antibody

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