APOBEC3A Polyclonal Antibody

Uniprot: P31941
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30528

      Synonyms:A3A,ABC3A,APOBEC3A,Apolipoprotein B mRNA editing enzyme,Apolipoprotein B mRNA editing enzyme,catalytic polypeptide like 3A,ARP3,bK150C2.1,Catalytic polypeptide like 3A,Phorbolin 1,Phorbolin-1,PHRBN,Probable DNA dC >dU editing enzyme APOBEC-3A,Probable DNA dC->dU-editing enzyme APOBEC-3A

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms A3A,ABC3A,APOBEC3A,Apolipoprotein B mRNA editing enzyme,Apolipoprotein B mRNA editing enzyme,catalytic polypeptide like 3A,ARP3,bK150C2.1,Catalytic polypeptide like 3A,Phorbolin 1,Phorbolin-1,PHRBN,Probable DNA dC >dU editing enzyme APOBEC-3A,Probable DNA dC->dU-editing enzyme APOBEC-3A
      Swissprot P31941
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the Internal region of human APOBEC3A
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:10000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus,Other locations:cytoplasm
      Tissue specificity Expressed in peripherical leukocytes and keratinocytes.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.APOBEC3A (Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 3A) is a Protein Coding gene. Among its related pathways are mRNA Editing- C to U Conversion and Gene Expression. GO annotations related to this gene include hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines and deoxycytidine deaminase activity. An important paralog of this gene is APOBEC3B.

      Images

      Western Blot analysis of Jurkat cells with APOBEC3A Polyclonal Antibody.

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