APPL1 Polyclonal Antibody

Uniprot: Q9UKG1
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30535

      Synonyms:Adapter protein containing PH domain,Adaptor Protein Containing pH Domain,Adaptor protein containing pH domain PTB domain and leucine zipper motif 1,Adaptor protein containing pH domain PTB domain and leucine zipper motif,Adaptor protein phosphotyrosine interacting with PH domain and leucine zipper 1,AKT2 INTERACTOR,APPL 1,Appl1,DCC interacting protein 13 alpha,DCC-interacting protein 13-alpha,DIP 13 alpha,DIP13 alpha,Dip13-alpha,DIP13alpha,DP13A,KIAA1428,PTB domain and leucine zipper motif 1,PTB Domain and Leucine Zipper Motif,Signaling adaptor protein DIP13alpha

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Adapter protein containing PH domain,Adaptor Protein Containing pH Domain,Adaptor protein containing pH domain PTB domain and leucine zipper motif 1,Adaptor protein containing pH domain PTB domain and leucine zipper motif,Adaptor protein phosphotyrosine interacting with PH domain and leucine zipper 1,AKT2 INTERACTOR,APPL 1,Appl1,DCC interacting protein 13 alpha,DCC-interacting protein 13-alpha,DIP 13 alpha,DIP13 alpha,Dip13-alpha,DIP13alpha,DP13A,KIAA1428,PTB domain and leucine zipper motif 1,PTB Domain and Leucine Zipper Motif,Signaling adaptor protein DIP13alpha
      Swissprot Q9UKG1
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthesized peptide derived from the Internal region of human APPL1
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Early endosome membrane. Nucleus. Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.
      Tissue specificity High levels in heart, ovary, pancreas and skeletal muscle.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

      Images

      Western Blot analysis of A549 cells with APPL1 Polyclonal Antibody.

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