AVEN Polyclonal Antibody

Uniprot: Q9NQS1
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30612

      Synonyms:1700013A01Rik,1700056A21Rik,Apoptosis caspase activation inhibitor,AVEN,AVEN,Cell death regulator Aven,mAven L,mAven S,MGC124011,OTTMUSP00000016129,PDCD12,Programmed cell death 12,RP23-52C15.2

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,Mk

      Applications: WB,IHC-p,IF,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms 1700013A01Rik,1700056A21Rik,Apoptosis caspase activation inhibitor,AVEN,AVEN,Cell death regulator Aven,mAven L,mAven S,MGC124011,OTTMUSP00000016129,PDCD12,Programmed cell death 12,RP23-52C15.2
      Swissprot Q9NQS1
      Source Rabbit
      Reactivity Human,Monkey
      Immunogen Synthesized peptide derived from the C-terminal region of human Aven
      Application WB,IHC-p,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Endomembrane system. Associated with intracellular membranes.
      Tissue specificity Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background Aven binds to both Bcl-x(L) and the caspase regulator Apaf-1,which can supported that Bcl-x(L) inhibits cell death at a late (postmitochondrial) step in the death pathway.Identified in a yeast two-hybrid screen,Aven inhibited the proteolytic activation of caspases in a cell-free extract and suppressed apoptosis induced by Apaf-1 plus caspase-9. Expressing highly in the testis, ovary, and thymus .

      Images

      Western Blot analysis of COS7 cells with Aven Polyclonal Antibody.

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