CAPN10 Polyclonal Antibody

Uniprot: Q9HC96
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30724

      Synonyms:Calcium activated neutral protease,Calcium activated neutral proteinase 10,Calcium-activated neutral proteinase 10,calpain like protease CAPN10,Calpain-10,Calpain10,CAN10,CANP 10,CANP10,CAPN 10,CAPN10,EC 3.4.22.,KIAA1845,NIDDM1

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Calcium activated neutral protease,Calcium activated neutral proteinase 10,Calcium-activated neutral proteinase 10,calpain like protease CAPN10,Calpain-10,Calpain10,CAN10,CANP 10,CANP10,CAPN 10,CAPN10,EC 3.4.22.,KIAA1845,NIDDM1
      Swissprot Q9HC96
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the N-terminal region of human Calpain 10.
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytosol,Mitochondrion,Plasma Membrane
      Tissue specificity Ubiquitous.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.

      Images

      Western Blot analysis of LOVO cells with CAPN10 Polyclonal Antibody

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