CAPN9 Polyclonal Antibody

Uniprot: O14815
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30727

      Synonyms:Calpain-9,Calpain9,CAN9,CAPN 9,CAPN9,CG36 protein,Digestive tract specific calpain,Digestive tract-specific calpain,GC36,nCL-4,nCL4,New calpain 4,novel calpain large subunit-4,novel calpain large subunit4,OTTHUMP00000035899,OTTHUMP00000035900,Protein CG36

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Calpain-9,Calpain9,CAN9,CAPN 9,CAPN9,CG36 protein,Digestive tract specific calpain,Digestive tract-specific calpain,GC36,nCL-4,nCL4,New calpain 4,novel calpain large subunit-4,novel calpain large subunit4,OTTHUMP00000035899,OTTHUMP00000035900,Protein CG36
      Swissprot O14815
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the Internal region of human Calpain 9
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:5000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Other locations:cytoplasm
      Tissue specificity Expressed predominantly in stomach.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.CAPN9 (Calpain 9) is a Protein Coding gene. Diseases associated with CAPN9 include Gastric Cancer. Among its related pathways are Degradation of the extracellular matrix and Arrhythmogenic right ventricular cardiomyopathy (ARVC). GO annotations related to this gene include calcium ion binding and calcium-dependent cysteine-type endopeptidase activity. An important paralog of this gene is CAPN3.

      Images

      Western Blot analysis of HuvEc cells with CAPN9 Polyclonal Antibody

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