CCKBR Polyclonal Antibody

Uniprot: P32239
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30795

      Synonyms:CCK B,CCK B receptor,CCK BR,CCK-B receptor,CCK-BR,CCK2 R,CCK2 receptor,CCK2-R,CCKB,CCKB receptor,CCKBR,CCKR Type B,CCKRB,Cholecystokinin 2 receptor,Cholecystokinin B receptor,Cholecystokinin-2 receptor,Cholecystokinin2 receptor,CholecystokininB receptor,GASR,GASR,Gastrin receptor,Gastrin/cholecystokinin type B receptor,Gastrin\cholecystokinin brain receptor

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R,Mk

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CCK B,CCK B receptor,CCK BR,CCK-B receptor,CCK-BR,CCK2 R,CCK2 receptor,CCK2-R,CCKB,CCKB receptor,CCKBR,CCKR Type B,CCKRB,Cholecystokinin 2 receptor,Cholecystokinin B receptor,Cholecystokinin-2 receptor,Cholecystokinin2 receptor,CholecystokininB receptor,GASR,GASR,Gastrin receptor,Gastrin/cholecystokinin type B receptor,Gastrin\cholecystokinin brain receptor
      Swissprot P32239
      Source Rabbit
      Reactivity Human,Mouse,Rat,Monkey
      Immunogen Synthesized peptide derived from the N-terminal region of human CCK-BR
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane.
      Tissue specificity Isoform 1 is expressed in brain, pancreas, stomach, the colon cancer cell line LoVo and the T-lymphoblastoma Jurkat, but not in heart, placenta, liver, lung, skeletal muscle, kidney or the stomach cancer cell line AGS. Expressed at high levels in the small cell lung cancer cell line NCI-H510, at lower levels in NCI-H345, NCI-H69 and GLC28 cell lines, not expressed in GLC19 cell line. Within the stomach, expressed at high levels in the mucosa of the gastric fundus and at low levels in the antrum and duodenum. Isoform 2 is present in pancreatic cancer cells and colorectal cancer cells, but not in normal pancreas or colonic mucosa. Isoform 3 is expressed in brain, pancreas, stomach, the stomach cancer cell line AGS and the colon cancer cell line LoVo.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.

      Images

      Western Blot analysis of A549 cells with CCKBR Polyclonal Antibody

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