CD156c Polyclonal Antibody

Uniprot : O14672
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14498

      Synonyms:A disintegrin and metalloprotease domain 10,A disintegrin and metalloproteinase domain 10,AD 10,AD10,AD18,ADA10,ADAM 10,ADAM metallopeptidase domain 10,ADAM10,CD 156c,CD156c,CD156c antigen,CDw156,disintegrin and metalloproteinase domain containing protein 10,Disintegrin and metalloproteinase domain-containing protein 10,HsT 18717,HsT18717,Kuz,Kuzbanian,Kuzbanian protein homolog,Kuzbanian,Drosophila,homolog of,MADM,Mammalian disintegrin metalloprotease,Mammalian disintegrin-metalloprotease,RAK

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms A disintegrin and metalloprotease domain 10,A disintegrin and metalloproteinase domain 10,AD 10,AD10,AD18,ADA10,ADAM 10,ADAM metallopeptidase domain 10,ADAM10,CD 156c,CD156c,CD156c antigen,CDw156,disintegrin and metalloproteinase domain containing protein 10,Disintegrin and metalloproteinase domain-containing protein 10,HsT 18717,HsT18717,Kuz,Kuzbanian,Kuzbanian protein homolog,Kuzbanian,Drosophila,homolog of,MADM,Mammalian disintegrin metalloprotease,Mammalian disintegrin-metalloprotease,RAK
      Swissprot O14672
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human ADAM10
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:200-1:1000, IHC 1:25-1:100
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane. Endomembrane system. Is localized in the plasma membrane but is predominantly expressed in the Golgi apparatus and in released membrane vesicles derived likely from the Golgi.
      Tissue specificity Expressed in spleen, lymph node, thymus, peripheral blood leukocyte, bone marrow, cartilage, chondrocytes and fetal liver.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP).

      Images

      Western Blot analysis of PC3 cell using CD156c Polyclonal Antibody at dilution of 1:300

      Immunohistochemistry of paraffin-embedded Human thyroid cancer using CD156c Polyclonal Antibody at dilution of 1:30

      Immunohistochemistry of paraffin-embedded Human breast cancer using CD156c Polyclonal Antibody at dilution of 1:30

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