CDC6 Polyclonal Antibody

Uniprot : Q99741
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30859

      Synonyms:Cdc 18L,Cdc 6,CDC18 (cell division cycle 18,S.pombe,homolog) like,CDC18 (S.pombe),Cdc18 related protein,CDC18(S.pombe),Cdc18-related protein,Cdc18L,cdc6,CDC6 cell division cycle 6 homolog,CDC6 related protein,CDC6-related protein,CDC6,Cdc6p,CELL CYCLE CONTROLLER CDC6,Cell division control protein 6,Cell division control protein 6 homolog,Cell division cycle 6 homolog (S. cerevisiae),Cell division cycle 6 homolog,Cell division cycle 6,S. cerevisiae,homolog of,HsCDC 6,HsCDC18,HsCDC6,p62,p62(cdc 6),p62(cdc6)

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC-p,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Cdc 18L,Cdc 6,CDC18 (cell division cycle 18,S.pombe,homolog) like,CDC18 (S.pombe),Cdc18 related protein,CDC18(S.pombe),Cdc18-related protein,Cdc18L,cdc6,CDC6 cell division cycle 6 homolog,CDC6 related protein,CDC6-related protein,CDC6,Cdc6p,CELL CYCLE CONTROLLER CDC6,Cell division control protein 6,Cell division control protein 6 homolog,Cell division cycle 6 homolog (S. cerevisiae),Cell division cycle 6 homolog,Cell division cycle 6,S. cerevisiae,homolog of,HsCDC 6,HsCDC18,HsCDC6,p62,p62(cdc 6),p62(cdc6)
      Swissprot Q99741
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthesized peptide derived from human Cdc6 around the non-phosphorylation site of S54.
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus. Cytoplasm. The protein is nuclear in G1 and cytoplasmic in S-phase cells.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

      Images

      Western Blot analysis of Hela cells with Cdc6 Polyclonal Antibody.

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