CHKB Polyclonal Antibody

Uniprot: Q9Y259
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30921

      Synonyms:CHKB,CHETK,CHKL,Choline/ethanolamine kinase,Choline kinase beta,CK,CKB,Choline kinase-like protein,Ethanolamine kinase,EK,Ethanolamine kinase beta,EKB,choline/ethanolamine kinase beta,CKEKB

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,IHC-p,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CHKB,CHETK,CHKL,Choline/ethanolamine kinase,Choline kinase beta,CK,CKB,Choline kinase-like protein,Ethanolamine kinase,EK,Ethanolamine kinase beta,EKB,choline/ethanolamine kinase beta,CKEKB
      Swissprot Q9Y259
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the C-terminal region of human ChoKB
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytosol
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background Choline kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to phosphocholine/phosphoethanolamine. This is the first enzyme in the biosynthesis of phosphatidylcholine/phosphatidylethanolamine in all animal cells. The highly purified CKs from mammalian sources and their recombinant gene products have been shown to have EK activity also, indicating that both activities reside on the same protein. The choline kinase-like protein encoded by CHKL belongs to the choline/ethanolamine kinase family; however, its exact function is not known. Read-through transcripts are expressed from this locus that include exons from the downstream CPT1B locus.CHKB (Choline Kinase Beta) is a Protein Coding gene. Diseases associated with CHKB include Muscular Dystrophy, Congenital, Megaconial Type and Chkb-Related Muscle Diseases. Among its related pathways are Synthesis of PC and Glycerophospholipid biosynthesis. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and choline kinase activity. An important paralog of this gene is CHKA.

      Images

      Western Blot analysis of HepG2 cells with CHKB Polyclonal Antibody

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