Claudin 19 Polyclonal Antibody

Uniprot: Q8N6F1
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30940

      Synonyms:CLDN19,Claudin-19

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CLDN19,Claudin-19
      Swissprot Q8N6F1
      Source Rabbit
      Reactivity Human,Rat
      Immunogen Synthesized peptide derived from the Internal region of human Claudin-19
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:10000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus,Plasma Membrane,basolateral plasma membrane,Other locations:apical junction complex,bicellular tight junction,cytoplasm,integral component of membrane
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

      Images

      Western Blot analysis of Jurkat cells using Claudin 19 Polyclonal Antibody at dilution of 1:500.

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