Synonyms:Ceroid lipofuscinosis neuronal 5,Ceroid-lipofuscinosis neuronal protein 5,CLN5,CLN5,NCL,Protein CLN5
|Synonyms||Ceroid lipofuscinosis neuronal 5,Ceroid-lipofuscinosis neuronal protein 5,CLN5,CLN5,NCL,Protein CLN5|
|Immunogen||Synthesized peptide derived from the Internal region of human CLN5|
|Recommended dilution||WB 1:500-1:2000, ELISA 1:10000|
|Storage instructions||Store at -20℃. Avoid freeze / thaw cycles.|
|Storage buffer||PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4|
|Background||This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.|
Western Blot analysis of 293T cells using CLN5 Polyclonal Antibody at dilution of 1:1000.