COL4A6 Polyclonal Antibody

Uniprot : Q14031
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30993

      Synonyms:COL4A6,Collagen Alpha 6(IV),Collagen alpha 6(IV) chain,Collagen IV alpha 6 polypeptide,Collagen of basement membrane alpha 6,Collagen type IV alpha 6,dJ889N15.4,MGC88184,Type IV alpha 6 collagen

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,IHC-p,IF,ELISA

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      Overview

      Synonyms COL4A6,Collagen Alpha 6(IV),Collagen alpha 6(IV) chain,Collagen IV alpha 6 polypeptide,Collagen of basement membrane alpha 6,Collagen type IV alpha 6,dJ889N15.4,MGC88184,Type IV alpha 6 collagen
      Swissprot Q14031
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the C-terminal region of human COL4A6
      Application WB,IHC-p,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms.COL4A6 (Collagen Type IV Alpha 6 Chain) is a Protein Coding gene. Diseases associated with COL4A6 include Deafness, X-Linked 6 and X-Linked Non-Syndromic Sensorineural Deafness Type Dfn. Among its related pathways are Collagen chain trimerization and Phospholipase-C Pathway. GO annotations related to this gene include structural molecule activity and extracellular matrix structural constituent. An important paralog of this gene is COL4A2.

      Images

      Western Blot analysis of HepG2 cells using COL4A6 Polyclonal Antibody at dilution of 1:500.

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