COL5A3 Polyclonal Antibody

Uniprot : P25940
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30995

      Synonyms:COL5A3,Collagen alpha-3(V) chain

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,IHC-p,IF,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms COL5A3,Collagen alpha-3(V) chain
      Swissprot P25940
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the N-terminal region of human COL5A3
      Application WB,IHC-p,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Endoplasmic reticulum,endoplasmic reticulum lumen,Extracellular region or secreted,collagen type V trimer,extracellular exosome,extracellular matrix,extracellular region
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are thought to be responsible for the symptoms of a subset of patients with Ehlers-Danlos syndrome type III. Messages of several sizes can be detected in northern blots but sequence information cannot confirm the identity of the shorter messages.COL5A3 (Collagen Type V Alpha 3 Chain) is a Protein Coding gene. Diseases associated with COL5A3 include Ehlers-Danlos Syndrome, Type Iii. Among its related pathways are Collagen chain trimerization and Phospholipase-C Pathway. GO annotations related to this gene include heparin binding and extracellular matrix structural constituent. An important paralog of this gene is COL5A1.

      Images

      Western Blot analysis of 3T3 cells with COL5A3 Polyclonal Antibody.

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