FASTK Polyclonal Antibody

Uniprot : Q14296
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14079

      Synonyms:Fas activated serine threonine kinase,Fas-activated serine/threonine kinase,FAST,FAST kinase,FASTK,FASTK,FLJ13079

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Fas activated serine threonine kinase,Fas-activated serine/threonine kinase,FAST,FAST kinase,FASTK,FASTK,FLJ13079
      Swissprot Q14296
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human FASTK
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Mitochondrion,mitochondrial matrix
      Tissue specificity Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.

      Images

      Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using FASTK Polyclonal Antibody at dilution 1:30

      Immunohistochemistry of paraffin-embedded Human brain tissue using FASTK Polyclonal Antibody at dilution 1:30

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