EGFR,also named as ERBB1,is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12,encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression,including cell proliferation,apoptosis,angiogenesis,and metastatic spread. Mutations in this gene are associated with lung cancer.

Product Information

Synonyms	ErbB-1, ErbB1,ERBB, HER1, mENA
Swissprot	P00533
Reactivity	Human
Specificity	Detects Human EGFR in ELISAs
Buffer	Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% pro
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Expiration Date	12 months

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Human EGFR Antibody Pair Set

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Human EGFR Antibody Pair Set

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