Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule.

Product Information

Synonyms	F-TCF, HGFB, HPTA, SF, Scatter Factor, Hepapoietin A
Swissprot	P14210
Reactivity	Human
Specificity	Detects Human HGF in ELISAs
Buffer	Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% pro
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Expiration Date	12 months

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Human HGF Antibody Pair Set

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Human HGF Antibody Pair Set

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