IRF9 Polyclonal Antibody

Uniprot : Q00978
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14166

      Synonyms:IFN alpha responsive transcription factor subunit,IFN-alpha-responsive transcription factor subunit,Interferon regulatory factor 9,interferon stimulated transcription factor 3,Interferon-stimulated gene factor 3 gamma,interferon-stimulated transcription factor 3,gamma 48kDa,IRF 9,IRF-9,Irf9,IRF9,ISGF 3 gamma,ISGF-3 gamma,ISGF3,ISGF3 p48 subunit,ISGF3G,OTTHUMP00000164692,OTTHUMP00000164693,p48,Transcriptional regulator ISGF3 subunit gamma

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms IFN alpha responsive transcription factor subunit,IFN-alpha-responsive transcription factor subunit,Interferon regulatory factor 9,interferon stimulated transcription factor 3,Interferon-stimulated gene factor 3 gamma,interferon-stimulated transcription factor 3,gamma 48kDa,IRF 9,IRF-9,Irf9,IRF9,ISGF 3 gamma,ISGF-3 gamma,ISGF3,ISGF3 p48 subunit,ISGF3G,OTTHUMP00000164692,OTTHUMP00000164693,p48,Transcriptional regulator ISGF3 subunit gamma
      Swissprot Q00978
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human IRF9
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:200-1:1000, IHC 1:50-1:200
      Concentration 0.6 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Nucleus. Translocated into the nucleus upon activation by IFN-alpha/beta.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Interferon regulatory factor 9 is a protein that in humans is encoded by the IRF9 gene, previously known as ISGF3G. Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

      Images

      Western Blot analysis of Mouse panceas tissue and NIH/3T3 cell using IRF9 Polyclonal Antibody at dilution of 1:380

      Immunohistochemistry of paraffin-embedded Human tonsil using IRF9 Polyclonal Antibody at dilution of 1:50

      Immunohistochemistry of paraffin-embedded Human esophagus cancer using IRF9 Polyclonal Antibody at dilution of 1:50

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