KLF17 Polyclonal Antibody

Uniprot : Q5JT82
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14667

      Synonyms:FLJ40160,KLF17,KLF17,Krueppel like factor 17,Krueppel-like factor 17,Novel zinc finger protein,RP4 675G8.1,RP4675G8.1,Zfp393,Zinc finger protein 393,ZNF393

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms FLJ40160,KLF17,KLF17,Krueppel like factor 17,Krueppel-like factor 17,Novel zinc finger protein,RP4 675G8.1,RP4675G8.1,Zfp393,Zinc finger protein 393,ZNF393
      Swissprot Q5JT82
      Source Rabbit
      Reactivity Human
      Immunogen Recombinant protein of human KLF17
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:25-1:100
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background Krueppel-like factor 17 is a protein that in humans is encoded by the KLF17 gene. Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.

      Images

      Immunohistochemistry of paraffin-embedded Human colon cancer tissue using KLF17 Polyclonal Antibody at dilution 1:30

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using KLF17 Polyclonal Antibody at dilution 1:30

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