LILRB1 Polyclonal Antibody

Uniprot : Q8NHL6
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14169

      Synonyms:CD85,CD85 antigen,CD85 antigen like family member J,CD85 antigen-like family member J,CD85j,CD85j antigen,Ig like transcript 2,ILT 2,ILT-2,ILT2,immunoglobulin like transcript 2,Immunoglobulin-like transcript 2,leukocyte Ig like receptor 1,Leukocyte immunoglobulin like receptor 1,leukocyte immunoglobulin like receptor subfamily B member 1,Leukocyte immunoglobulin like receptor subfamily B member 1 precursor,leukocyte immunoglobulin like receptor subfamily B member 1 soluble isoform,leukocyte immunoglobulin like receptor,subfamily B,member 1,Leukocyte immunoglobulin-like receptor 1,Leukocyte immunoglobulin-like receptor subfamily B member 1,leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform,leukocyte immunoglobulin-like receptor,subfamily B (with TM and ITIM domains),member 1,LILRB1,LIR 1,LIR-1,LIR1,LIRB1,MIR 7,MIR-7,MIR7,Monocyte/macrophage immunoglobulin like receptor 7,Monocyte/macrophage immunoglobulin-like receptor 7,PIR B,PIRB

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CD85,CD85 antigen,CD85 antigen like family member J,CD85 antigen-like family member J,CD85j,CD85j antigen,Ig like transcript 2,ILT 2,ILT-2,ILT2,immunoglobulin like transcript 2,Immunoglobulin-like transcript 2,leukocyte Ig like receptor 1,Leukocyte immunoglobulin like receptor 1,leukocyte immunoglobulin like receptor subfamily B member 1,Leukocyte immunoglobulin like receptor subfamily B member 1 precursor,leukocyte immunoglobulin like receptor subfamily B member 1 soluble isoform,leukocyte immunoglobulin like receptor,subfamily B,member 1,Leukocyte immunoglobulin-like receptor 1,Leukocyte immunoglobulin-like receptor subfamily B member 1,leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform,leukocyte immunoglobulin-like receptor,subfamily B (with TM and ITIM domains),member 1,LILRB1,LIR 1,LIR-1,LIR1,LIRB1,MIR 7,MIR-7,MIR7,Monocyte/macrophage immunoglobulin like receptor 7,Monocyte/macrophage immunoglobulin-like receptor 7,PIR B,PIRB
      Swissprot Q8NHL6
      Source Rabbit
      Reactivity Human
      Immunogen Recombinant protein of human LILRB1
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Membrane.
      Tissue specificity Expressed predominantly on B-cells and monocytes, and at lower levels on dendritic cells. Detected on a low percentage of T-cells and natural killer (NK) cells.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using LILRB1 Polyclonal Antibody at dilution 1:30

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