CXCL16 is a recently discovered cytokine belonging to the CXC chemokine family,which is synthesised in plasmacytoid dendritic cell as a transmembrane molecule. It exists in a transmembrane and soluble form. The transmembrane form of CXCL16 functions as an adhesion molecule for CXCR6-expressing cells,whereas the soluble form of CXCL16 mediates infiltration of circulating cells into sites of injury. CXCL16,has been proposed as an important pathogenic mediator in inflammatory diseases,including rheumatoid arthritis,glomerulonephritis,or prostate cancer. CXCL16 has been implicated in some forms of renal disease such as lupus nephritis and antiglomerular basement membrane nephritis. CXCL16 also plays a pivotal role in the pathogenesis of angiotensin II–induced renal injury and fibrosis through regulation of macrophage and T cell infiltration and bone marrow–derived fibroblast accumulation.

Product Information

Synonyms	SCYB16, SR-PSOX, CXCLG16
Swissprot	Q8BSU2
Reactivity	Mouse
Specificity	Detects Mouse CXCL16 in ELISAs
Buffer	Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% pro
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Expiration Date	12 months

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Mouse CXCL16 Antibody Pair Set

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Mouse CXCL16 Antibody Pair Set

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