MSH4 Polyclonal Antibody

Uniprot : O15457
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14223

      Synonyms:hMSH4,MSH 4,MSH4,MSH4,MutS homolog 4 (E. Coli),MutS homolog 4,MutS protein homolog 4

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms hMSH4,MSH 4,MSH4,MSH4,MutS homolog 4 (E. Coli),MutS homolog 4,MutS protein homolog 4
      Swissprot O15457
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human MSH4
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:100-1:300
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus,recombination nodule,synaptonemal complex
      Tissue specificity Testis and ovary specific.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.

      Images

      Immunohistochemistry of paraffin-embedded Human colon cancer tissue using MSH4 Polyclonal Antibody at dilution 1:50

      Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MSH4 Polyclonal Antibody at dilution 1:50

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