MUC20 Polyclonal Antibody

Uniprot : Q8N307
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14228

      Synonyms:MUC 20,MUC-20,Muc20,MUC20,Mucin 20,Mucin 20,cell surface associated,Mucin-20,Transmembrane mucin MUC20S

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms MUC 20,MUC-20,Muc20,MUC20,Mucin 20,Mucin 20,cell surface associated,Mucin-20,Transmembrane mucin MUC20S
      Swissprot Q8N307
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human MUC20
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:25-1:100
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted. Apical cell membrane. Basolateral cell membrane. Cell projection>microvillus membrane.
      Tissue specificity Highly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules. Detected in most of the male urogenital tract epithelia, with the exception of epididymis.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene encodes a member of the mucin protein family. Mucins are higHuman, Mouseolecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies. Multiple transcript variants encoding different isoforms have been found for this gene.

      Images

      Western Blot analysis of Mouse eye tissue using MUC20 Polyclonal Antibody at dilution of 1:1400

      Immunohistochemistry of paraffin-embedded Human lung cancer using MUC20 Polyclonal Antibody at dilution of 1:40

      Immunohistochemistry of paraffin-embedded Human liver cancer using MUC20 Polyclonal Antibody at dilution of 1:40

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