Otocadherin Polyclonal Antibody

Uniprot : Q9H251
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14286

      Synonyms:Age related hearing loss 1,Ahl 1,Ahl,Ahl1,Bob,Bobby,Bus,Bustling,Cadherin 23,Cadherin23,CDH 23,Mdfw,Modifier of deaf waddler,nmf112,nmf181,nmf252,Otocadherin,USH 1D,USH1 D,USH1D,Waltzer

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Age related hearing loss 1,Ahl 1,Ahl,Ahl1,Bob,Bobby,Bus,Bustling,Cadherin 23,Cadherin23,CDH 23,Mdfw,Modifier of deaf waddler,nmf112,nmf181,nmf252,Otocadherin,USH 1D,USH1 D,USH1D,Waltzer
      Swissprot Q9H251
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human CDH23
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.1 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane; Single-pass type I membrane protein
      Tissue specificity Particularly strong expression in the retina. Found also in the cochlea.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.

      Images

      Immunohistochemistry of paraffin-embedded Human colon cancer tissue using Otocadherin Polyclonal Antibody at dilution 1:60

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using Otocadherin Polyclonal Antibody at dilution 1:60

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