p120 Polyclonal Antibody

Uniprot : O60716
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-32440

      Synonyms:Cadherin associated Src substrate,Cadherin-associated Src substrate,CAS,Catenin (cadherin associated protein) delta 1,Catenin delta 1,Catenin delta,Catenin delta-1,CTND1,CTNND 1,CTNND,CTNND1,KIAA0384,p120,P120 CAS,p120 catenin,P120 CTN,p120(cas),p120(ctn),P120CAS,P120CTN

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC-p,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Cadherin associated Src substrate,Cadherin-associated Src substrate,CAS,Catenin (cadherin associated protein) delta 1,Catenin delta 1,Catenin delta,Catenin delta-1,CTND1,CTNND 1,CTNND,CTNND1,KIAA0384,p120,P120 CAS,p120 catenin,P120 CTN,p120(cas),p120(ctn),P120CAS,P120CTN
      Swissprot O60716
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from human p120 around the non-phosphorylation site of Y228.
      Application WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
      Concentration 1 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
      Tissue specificity Expressed in vascular endothelium.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

      Images

      Western Blot analysis of HuvEc cells with p120 Polyclonal Antibody.

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