PIP5K1A Polyclonal Antibody

Uniprot : Q99755
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14699

      Synonyms:68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha,Phosphatidylinositol 4 phosphate 5 kinase type I alpha,Phosphatidylinositol-4-phosphate 5-kinase type I alpha,Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha,PI4P5K Ia,PI51A,PIP5K A,PIP5K1-alpha,Pip5k1a,PIP5KIalpha,PtdIns(4)P-5-kinase 1 alpha

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha,Phosphatidylinositol 4 phosphate 5 kinase type I alpha,Phosphatidylinositol-4-phosphate 5-kinase type I alpha,Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha,PI4P5K Ia,PI51A,PIP5K A,PIP5K1-alpha,Pip5k1a,PIP5KIalpha,PtdIns(4)P-5-kinase 1 alpha
      Swissprot Q99755
      Source Rabbit
      Reactivity Human
      Immunogen Recombinant protein of human PIP5K1A
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:200-1:1000, IHC 1:25-1:100
      Concentration 0.2 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane. Endomembrane system. Golgi apparatus>Golgi stack. Nucleus speckle. Associated with the plasma membrane and with internal membranes. Associated with Golgi stacks (By similarity). Detected on RAC1-induced plasma membrane ruffles, and on membrane ruffles induced by platelet-derived growth factor. Localizes to nuclear speckles and associates with TUT1 to regulate polyadenylation of selected mRNAs.
      Tissue specificity Highly expressed in heart, placenta, skeletal muscle, kidney and pancreas. Detected at lower levels in brain, lung and liver.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha is an enzyme that in humans is encoded by the PIP5K1A gene. Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). PtdIns(4,5)P2 is involved in a variety of cellular processes and is the substrate to form phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3), another second messenger. The majority of PtdIns(4,5)P2 is thought to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of PtdIns4P.

      Images

      Western Blot analysis of PC3 and 293T cell using PIP5K1A Polyclonal Antibody at dilution of 1:300

      Immunohistochemistry of paraffin-embedded Human thyroid cancer using PIP5K1A Polyclonal Antibody at dilution of 1:30

      Immunohistochemistry of paraffin-embedded Human brain using PIP5K1A Polyclonal Antibody at dilution of 1:30

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