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Recombinant Human PTEN Protein (His Tag)

Uniprot : P60484-1
  • Cat.No.:PKSH033828

  • Expression host: E.coli

To Purchase PKSH033828

Size:
  • 20µg
  • 100µg
Price: $99
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Description

Synonyms 10q23del; BZS; DEC; GLM2; MGC11227; MHAM; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; Phosphatase and tensin like protein; Phosphatidylinositol 3; 4; 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Pten; PTEN; PTEN1; TEP1
Species Human
Expression_host E.coli
Sequence Thr2-Val403
Accession P60484-1
Application Immunogen(E-AB-40284)
Mol_Mass 46.8 kDa
AP_Mol_Mass 49.1 kDa
Tag N-His

Properties

Purity >85 % as determined by reducing SDS-PAGE.
Endotoxin level Not tested.
Storage Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Formulation Lyophilized from sterile PBS, pH 7.4

Background

PTEN (also designated MMAC1),products of tumor suppressor genes,are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors,such as brain,breast,kidney and prostate cancers. PTEN is a protein tyrosine phosphatase that may terminate the signaling transduction pathways mediated by PI 3-kinase/Akt. PTEN has an apparent molecular weight of 55 kDa and it is located in the cytosol.

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