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Recombinant Mouse Cathepsin L/CTSL Protein (His Tag)

  • Cat.No.:PKSM041247

  • Expression host: Human Cells

To Purchase PKSM041247

Size:
  • 10μg
  • 50μg
Price: $178
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Description

Synonyms Cathepsin L1; Major excreted protein; p39 cysteine proteinase; Ctsl1;1190035F06Rik
Species Mouse
Expression_host Human Cells
Sequence Thr18-Asn334
Accession P06797
Mol_Mass 36.8 kDa
AP_Mol_Mass 13-40kDa
Tag C-6His

Properties

Purity > 95 % as determined by SDS-PAGE
Endotoxin level < 1.0 EU per μg as determined by the LAL method.
Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation LyopHilized from a 0.2 μM filtered solution of 20mM PB,150mM NaCl, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.

Background

Mouse Cathepsin L is a lysosomal cysteine proteinase which is a member of the peptidase C1 family. This protein is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Cathepsin L plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. Cathepsin L has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria.

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