SELPLG Polyclonal Antibody

Uniprot : Q14242
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14319

      Synonyms:CD 162,CD162,CD162 antigen,CLA,Cutaneous lymphocyte associated associated antigen,P selectin glycoprotein ligand 1,P selectin glycoprotein ligand 1 precursor,P-selectin glycoprotein ligand 1,PSGL 1,PSGL-1,PSGL1,Selectin P ligand,SELPL,SELPLG

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CD 162,CD162,CD162 antigen,CLA,Cutaneous lymphocyte associated associated antigen,P selectin glycoprotein ligand 1,P selectin glycoprotein ligand 1 precursor,P-selectin glycoprotein ligand 1,PSGL 1,PSGL-1,PSGL1,Selectin P ligand,SELPL,SELPLG
      Swissprot Q14242
      Source Rabbit
      Reactivity Human
      Immunogen Recombinant protein of human SELPLG
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Membrane.
      Tissue specificity Expressed on neutrophils, monocytes and most lymphocytes.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

      Images

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using SELPLG Polyclonal Antibody at dilution 1:50

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using SELPLG Polyclonal Antibody at dilution 1:50

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