NME1 Polyclonal Antibody
- +2
Price: $ 530
Price: $ 320
Price: $ 200
Size:
200μL
120μL
60μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse;Rat
- Applications: IHC;IF
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Product Details
Verified Samples |
Verified Samples in IHC:Rat heart,Mouse brain Verified Samples in IF:C6, HeLa |
Dilution |
IHC 1:50-1:200, IF 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | A synthetic peptide of human NME1 (NP_000260.1). |
Abbre | NME1 |
Synonyms | NME1;AWD;GAAD;NB;NBS;NDKA;NDPK-A;NDPKA;NM23;NM23-H1 |
Swissprot | |
Cellular Localization | Cytoplasm. Nucleus. Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA. |
Concentration | 1mg/mL |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method | Affinity purification |
Research Areas | Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Ice bag |
background | This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol