Alternate Names	Integrin alpha-V,αV integrin,Vitronectin Receptor,Integrin αV chain,ITGAV
Swissprot	P43406
Gene ID	16410
References	1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Maxfield SR, et al. 1989. J. Exp. Med. 169:2173. 3. Piali L, et al. 1995. J. Cell Biol. 130:451.

Product Details

Form	Liquid
Clone No.	RMV-7(See Other Available Formats)
Host	Rat
Isotype	Rat IgG1, κ
Isotype Control	Biotin Rat IgG1, κ Isotype Control[HRPN] [Product E-AB-F09823B]
Reactivity	Mouse
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	Biotin

How to select the appropriate detection channel through the spectrogram?

Background

CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
PE Anti-Mouse CD51 Antibody[RMV-7]	50Tests, 100Tests, 100Tests×2	Check More
APC Anti-Mouse CD51 Antibody[RMV-7]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine7 Anti-Mouse CD51 Antibody[RMV-7]	50Tests, 100Tests, 100Tests×2	Check More
PE Anti-Mouse CD51 Antibody[RMV-7]	25μg, 100μg	Check More
APC Anti-Mouse CD51 Antibody[RMV-7]	25μg, 100μg	Check More
PE/Cyanine7 Anti-Mouse CD51 Antibody[RMV-7]	25μg, 100μg	Check More

Citations

Reviews/Q&A

Show all
Reviews
Q&A

... Show All Show Less

*Product Name:
*Catalog Number:
*Name:
*Email:
*Message:
*Country:
*When will you use it?	Within 1 month In 2 to 3 month In 4 to 6 month 6 months later
*Captcha:	Click to load Captcha