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PE/Cyanine7 Anti-Human CD183/CXCR3 Antibody[G025H7]

Uniprot : P49682

Cat.No.:E-AB-F1156H
Applications: FCM
Isotype: Mouse IgG1, κ
Host: Mouse

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Price: $115

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Antigen Details

Alternate Names	CXCR3,GPR9,CXC-R3,CXCR-3,CKR-L2
Swissprot	P49682
References	1. Loetscher M, et al. 1996. J. Exp. Med. 184:963. 2. Cole KE, et al. 1998. J. Exp. Med. 187:2009. 3. Aksoy MO, et al. 2006. Am. J. Physiol. Lung Cell Mol. Physiol. 290:L909. 4. Curbishley SM, et al. 2005. Am. J. Pathol. 167:887. 5. Turner JE, et al. 2007. Mini. Rev. Med. Chem. 7:1089. 6. Wenzel J, et al. 2008. J. Invest. Dermatol. 128:67.

Product Details

Form	Liquid
Clone No.	G025H7
Host	Mouse
Isotype	Mouse IgG1, κ
Isotype Control	PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792H]
Reactivity	Human
Application	FCM
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	PE/Cyanine7
	PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter).

How to select the appropriate detection channel through the spectrogram?

Background

Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T cells (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
FITC Anti-Human CD183/CXCR3 Antibody[G025H7]	20Tests, 100Tests, 100Tests×2	Check More
PE Anti-Human CD183/CXCR3 Antibody[G025H7]	20Tests, 100Tests, 100Tests×2	Check More
APC Anti-Human CD183/CXCR3 Antibody[G025H7]	20Tests, 100Tests, 100Tests×2	Check More

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