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Cat.No.:E-AB-F1163H
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Alternate Names | EpCAM,Ep-CAM,GA733-2,M1S2,M4S1,MIC18,TACSTD1, TROP1 |
Swissprot | P16422 |
References |
1. Strnad J, et al. 1989. Cancer Res. 49:314.
2. Munz M, et al. 2004. Oncogene 23:5748. 3. Rao CG, et al. 2005. Int. J. Oncol. 27:49. |
Form | Liquid |
Clone No. | 9C4(See Other Available Formats) |
Host | Mouse |
Isotype | Mouse IgG2b, κ |
Isotype Control | PE/Cyanine7 Mouse IgG2b, κ Isotype Control[MPC-11] [Product E-AB-F09812H] |
Reactivity | Human |
Application | FCM (See the Application Description) |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Recommended Use | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Shipping | Biological ice pack at 4℃ |
Stability & Storage | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Conjugation | PE/Cyanine7 |
PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). | |
How to select the appropriate detection channel through the spectrogram?
CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas. |
Related Protocols | Staining Cell Surface Targets for Flow Cytometry |
Troubleshooting |
Product Name | Sizes | Price |
FITC Anti-Human CD326/EpCAM Antibody[9C4] | 20Tests, 100Tests, 100Tests×2 | Check More |
PE Anti-Human CD326/EpCAM Antibody[9C4] | 20Tests, 100Tests, 100Tests×2 | Check More |
APC Anti-Human CD326/EpCAM Antibody[9C4] | 20Tests, 100Tests, 100Tests×2 | Check More |
PE/Cyanine5 Anti-Human CD326/EpCAM Antibody[9C4] | 20Tests, 100Tests, 100Tests×2 | Check More |
Elab Fluor® Violet 450 Anti-Human CD326/EpCAM Antibody[9C4] | 20Tests, 100Tests, 100Tests×2 | Check More |