Recombinant 2019-nCoV NP (Truncated) (His Tag)(Active)

    • Recombinant 2019-nCoV NP (Truncated) (His Tag)(Active)
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    • Recombinant 2019-nCoV NP (Truncated) (His Tag)(Active)
    • Recombinant 2019-nCoV NP (Truncated) (His Tag)(Active)

      Catalog number:PKSR030537

      Synonyms:2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein

      Size:
      • 1mg
      Qty:
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      Price: $680

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      Overview

      Synonyms 2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein
      Species virus
      Expression_host E.coli
      Accession QHD43423.2
      Mol_Mass 36.2kDa
      Tag N-6His
      Bio_Activity Immobilized Recombinant 2019-nCoV NP (Truncated)(Cat#DRA58) at 2μg/ml (100 μl/well) can bind Anti-2019-nCoV NP Antibody (6G9)(Cat#DA027), the ED50 for this effect is 4.8 ng/ml.

      Properties

      Purity > 95 % as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per µg as determined by the LAL method.
      Storage Store at < -20°C, stable for 7 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μM filtered solution of PBS, pH 7.4.

      Background

      Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
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