Recombinant 2019-nCoV Nucleoprotein / NP Protein (His Tag)

    • Recombinant 2019-nCoV Nucleoprotein / NP Protein (His Tag)-Elabscience
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    • Recombinant 2019-nCoV Nucleoprotein / NP Protein (His Tag)-Elabscience
    • Recombinant 2019-nCoV Nucleoprotein / NP Protein (His Tag)-Elabscience

      Catalog number:PKSR030506

      Synonyms:2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein

      Size:
      • 100µg
      Qty:
      - +
      Price: $1084

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms 2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein
      Species virus
      Expression_host Baculovirus-Insect Cells
      Sequence Met1-Ala422
      Accession NP_828858.1
      Application Immunogen(E-AB-V1013,E-AB-V1014)
      Mol_Mass 47.5 kDa
      AP_Mol_Mass 47.1 kDa
      Tag C-His

      Properties

      Purity > 80 % as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per µg as determined by the LAL method.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

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