Recombinant Human EphB1/EPHT2 Protein (aa 564-984, His Tag)(Active)

    • Recombinant Human EphB1 / EPHT2 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human EphB1 / EPHT2 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human EphB1 / EPHT2 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033688

      Synonyms:Ephrin Type-B Receptor 1; ELK; EPH Tyrosine Kinase 2; EPH-Like Kinase 6; EK6; hEK6; Neuronally-Expressed EPH; Related Tyrosine Kinase; NET; Tyrosine-Protein Kinase Receptor EPH-2; EPHB1; ELK; EPHT2; HEK6

      Size:
      • 10μg
      • 50μg
      Qty:
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      Price: $117

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      Overview

      Synonyms Ephrin Type-B Receptor 1; ELK; EPH Tyrosine Kinase 2; EPH-Like Kinase 6; EK6; hEK6; Neuronally-Expressed EPH; Related Tyrosine Kinase; NET; Tyrosine-Protein Kinase Receptor EPH-2; EPHB1; ELK; EPHT2; HEK6
      Species Human
      Expression_host Human Cells
      Sequence Ser564-Ala984
      Accession P54762
      Application Functional ELISA
      Mol_Mass 48.8 kDa
      AP_Mol_Mass 49 kDa
      Tag C-His
      Bio_Activity Immobilized Human EphB1-His at 10μg/ml(100 μl/well) can bind Mouse EFNB2-Fc(Cat: PKSM041012). The ED50 of Human EphB1-His is 53.1 ug/ml .

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.

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      MSDS for ELISA ISO 9001

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