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Recombinant Human Galectin-1/LGALS1 Protein (His Tag)

Uniprot : P09382

Cat.No.:PKSH032471
Expression host: E.coli

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Description

Synonyms	Galectin-1;Gal-1;14 kDa Laminin-Binding Protein;HLBP14;14 kDa Lectin;Beta-Galactoside-Binding Lectin L-14-I;Galaptin;HBL;HPL;Lactose-Binding Lectin 1;Lectin Galactoside-Binding Soluble 1;Putative MAPK-Activating Protein PM12;S-Lac Lectin 1;LGALS1;GAL1;GBP
Species	Human
Expression_host	E.coli
Sequence	Ala2-Asp135
Accession	P09382
Mol_Mass	15.5 kDa
AP_Mol_Mass	15 kDa
Tag	N-His
Bio_Activity	Measured by its ability to agglutinate human red blood cells.The ED₅₀ for this effect is <2 μg/mL.

Properties

Purity	> 98 % as determined by reducing SDS-PAGE.
Endotoxin level	< 0.1 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domains. Galectin-1 can binds LGALS3BP and interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Galectin-1 may act as an autocrine negative growth factor which regulates apoptosis, cell proliferation and cell differentiation. In addition, Galectin-1 plays improtant roles in immunosuppressive and antiinflammatory properties.

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