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Recombinant Human Leukocyte Ig-Like Receptor B1/ LILRB1/ILT2/CD85j (C-6His-Avi) Biotinylated

Uniprot : D9IDM8

Cat.No.:PKSH034002
Expression host: HEK293 Cells

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Description

Synonyms	Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1;LIR-1;Leukocyte Immunoglobulin-Like Receptor 1;CD85 Antigen-Like Family Member J;Immunoglobulin-Like Transcript 2;ILT-2;Monocyte/Macrophage Immunoglobulin-Like Receptor 7;MIR-7;CD85j;LILRB1;ILT2;LIR1;MIR7
Species	Human
Expression_host	HEK293 Cells
Sequence	Gly24-His458
Accession	D9IDM8
Mol_Mass	50.0 kDa
AP_Mol_Mass	70-90 kDa
Tag	C-His-Avi

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR)) can be activating and inhibitory immunoreceptors. ILTs are expressed on many leukocyte subsets and regulators of immune responses . ILTs share significant homology with killer cell Ig-like receptors (KIR). Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains . ILT2 is expressed on most monocytes,dendritic cells,and mature B cells. ILT2 is also expressed on small percentages of T-cells and NK cells. ILT2 can prevents cellular activation.

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