Recombinant Human RSK3 / RPS6KA2 Protein (GST tag)

    • Recombinant Human RSK3 / RPS6KA2 Protein (GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Human RSK3 / RPS6KA2 Protein (GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Human RSK3 / RPS6KA2 Protein (GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSH030377

      Synonyms:HU-2;MAPKAPK1C;p90-RSK3;pp90RSK3;RSK;RSK3;S6K-alpha;S6K-alpha2

      Size:
      • 20µg
      • 50µg
      Qty:
      - +
      Price: $486

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms HU-2;MAPKAPK1C;p90-RSK3;pp90RSK3;RSK;RSK3;S6K-alpha;S6K-alpha2
      Species Human
      Expression_host Baculovirus-Insect Cells
      Sequence Met 1-Leu 733
      Accession Q15349-1
      Mol_Mass 110 kDa
      AP_Mol_Mass 110 kDa
      Tag N-GST
      Bio_Activity The specific activity was determined to be 41 nmol/min/mg using synthetic RSK peptide (KRRRLSSLRA) as substrate.

      Properties

      Purity > 84 % as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per µg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as sterile 20mM Tris, 500mM NaCl, pH 7.0, 20mM GSH
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Ribosomal protein S6 kinase alpha-2, also known as 90 kDa ribosomal protein S6 kinase 2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, Ribosomal S6 kinase 3, RSK-3, RPS6KA2 and MAPKAPK1C, is a nucleus protein which belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and S6 kinase subfamily. RPS6KA2 / RSK-3 is expressed in many tissues. Highest expression is in lung and skeletal muscle. The expression of RPS6KA2 reduced proliferation, caused G1 arrest, increased apoptosis, reduced levels of phosphorylated extracellular signal-regulated kinase and altered other cell cycle proteins. RPS6KA2 / RSK-3 contains one AGC-kinase C-terminal domain and two protein kinase domains. It forms a complex with either ERK1 or ERK2 in quiescent cells. It transiently dissociates following mitogenic stimulation. RPS6KA2 / RSK-3 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB. RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 are involved in several pathways central to the carcinogenic process, including regulation of cell growth, insulin, and inflammation. 

      SDS-PAGE

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      MSDS for ELISA

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