Recombinant Human SRC Kinase / Proto-oncogene c-Src Protein (His & GST tag)

    • Recombinant Human SRC Kinase / Proto-oncogene c-Src Protein (His & GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Human SRC Kinase / Proto-oncogene c-Src Protein (His & GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Human SRC Kinase / Proto-oncogene c-Src Protein (His & GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSH030385

      Synonyms:ASV;c-SRC;p60-Src;SRC1

      Size:
      • 20µg
      • 50µg
      Qty:
      - +
      Price: $486

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms ASV;c-SRC;p60-Src;SRC1
      Species Human
      Expression_host Baculovirus-Insect Cells
      Sequence Met 1-Leu 536
      Accession P12931-1
      Mol_Mass 87.7 kDa
      AP_Mol_Mass 81 kDa
      Tag N-His & GST
      Bio_Activity The specific activity was determined to be >80 nmol/min/mg using Poly(Glu:Tyr) 4:1 as substrate.

      Properties

      Purity > 90 % as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per µg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as sterile 50mM Tris, 100mM NaCl, pH 8.0, 20% gly, 0.3mM DTT
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C-SRC and V-SRC. C-SRC is only activated under certain circumstances where it is required such as growth factor signaling, while V-SRC is a constitutively active as opposed to normal SRC (C-SRC). Thus, V-SRC is an instructive example of an oncogene protein kinase whereas C-SRC is a proto-oncogene protein kinase. Inhibition of SRC with NR2A tyrosine phosphorylation mediated by PSD-95 may contribute to the lithium-induced downregulation of NMDA receptor function and provide neuroprotection against excitotoxicity.

      SDS-PAGE

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      MSDS for ELISA

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